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Mechanoacoustic sensing of physiological processes and body motions via a soft wireless device placed at the suprasternal notch

Skin-mounted soft electronics incorporating high-bandwidth triaxial accelerometers can provide broad classes of physiologically relevant information, such as mechanoacoustic signatures of underlying body processes (such as those captured by a stethoscope) and precision kinematics of core body motion...

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Autores principales: Lee, KunHyuck, Ni, Xiaoyue, Lee, Jong Yoon, Arafa, Hany, Pe, David J., Xu, Shuai, Avila, Raudel, Irie, Masahiro, Lee, Joo Hee, Easterlin, Ryder L, Kim, Dong Hyun, Chung, Ha Uk, Olabisi, Omolara O, Getaneh, Selam, Chung, Esther, Hill, Marc, Bell, Jeremy, Jang, Hokyung, Liu, Claire, Park, Jun Bin, Kim, Jungwoo, Kim, Sung Bong, Mehta, Sunita, Pharr, Matt, Tzavelis, Andreas, Reeder, Jonathan T., Huang, Ivy, Deng, Yujun, Xie, Zhaoqian, Davies, Charles R., Huang, Yonggang, Rogers, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035153/
https://www.ncbi.nlm.nih.gov/pubmed/31768002
http://dx.doi.org/10.1038/s41551-019-0480-6
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author Lee, KunHyuck
Ni, Xiaoyue
Lee, Jong Yoon
Arafa, Hany
Pe, David J.
Xu, Shuai
Avila, Raudel
Irie, Masahiro
Lee, Joo Hee
Easterlin, Ryder L
Kim, Dong Hyun
Chung, Ha Uk
Olabisi, Omolara O
Getaneh, Selam
Chung, Esther
Hill, Marc
Bell, Jeremy
Jang, Hokyung
Liu, Claire
Park, Jun Bin
Kim, Jungwoo
Kim, Sung Bong
Mehta, Sunita
Pharr, Matt
Tzavelis, Andreas
Reeder, Jonathan T.
Huang, Ivy
Deng, Yujun
Xie, Zhaoqian
Davies, Charles R.
Huang, Yonggang
Rogers, John A.
author_facet Lee, KunHyuck
Ni, Xiaoyue
Lee, Jong Yoon
Arafa, Hany
Pe, David J.
Xu, Shuai
Avila, Raudel
Irie, Masahiro
Lee, Joo Hee
Easterlin, Ryder L
Kim, Dong Hyun
Chung, Ha Uk
Olabisi, Omolara O
Getaneh, Selam
Chung, Esther
Hill, Marc
Bell, Jeremy
Jang, Hokyung
Liu, Claire
Park, Jun Bin
Kim, Jungwoo
Kim, Sung Bong
Mehta, Sunita
Pharr, Matt
Tzavelis, Andreas
Reeder, Jonathan T.
Huang, Ivy
Deng, Yujun
Xie, Zhaoqian
Davies, Charles R.
Huang, Yonggang
Rogers, John A.
author_sort Lee, KunHyuck
collection PubMed
description Skin-mounted soft electronics incorporating high-bandwidth triaxial accelerometers can provide broad classes of physiologically relevant information, such as mechanoacoustic signatures of underlying body processes (such as those captured by a stethoscope) and precision kinematics of core body motions. Here, we describe a wireless device designed to be conformally placed on the suprasternal notch for the continuous measurement of mechanoacoustic signals, from subtle vibrations of the skin at accelerations of ~10(−3) m·s(−2) to large motions of the entire body at ~10 m·s(−2), and at frequencies up to ~800 Hz. Because th measurements are a complex superposition of signals that arise from locomotion, body orientation, swallowing, respiration, cardiac activity, vocal-fold vibrations and other sources, we used frequency-domain analysis and machine learning to obtain, from human subjects during natural daily activities and exercise, real-time recordings of heart rate, respiration rate, energy intensity and other essential vital signs, as well as talking time and cadence, swallow counts and patterns, and other unconventional biomarkers. We also used the device in sleep laboratories, and validated the measurements via polysomnography.
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spelling pubmed-70351532020-05-25 Mechanoacoustic sensing of physiological processes and body motions via a soft wireless device placed at the suprasternal notch Lee, KunHyuck Ni, Xiaoyue Lee, Jong Yoon Arafa, Hany Pe, David J. Xu, Shuai Avila, Raudel Irie, Masahiro Lee, Joo Hee Easterlin, Ryder L Kim, Dong Hyun Chung, Ha Uk Olabisi, Omolara O Getaneh, Selam Chung, Esther Hill, Marc Bell, Jeremy Jang, Hokyung Liu, Claire Park, Jun Bin Kim, Jungwoo Kim, Sung Bong Mehta, Sunita Pharr, Matt Tzavelis, Andreas Reeder, Jonathan T. Huang, Ivy Deng, Yujun Xie, Zhaoqian Davies, Charles R. Huang, Yonggang Rogers, John A. Nat Biomed Eng Article Skin-mounted soft electronics incorporating high-bandwidth triaxial accelerometers can provide broad classes of physiologically relevant information, such as mechanoacoustic signatures of underlying body processes (such as those captured by a stethoscope) and precision kinematics of core body motions. Here, we describe a wireless device designed to be conformally placed on the suprasternal notch for the continuous measurement of mechanoacoustic signals, from subtle vibrations of the skin at accelerations of ~10(−3) m·s(−2) to large motions of the entire body at ~10 m·s(−2), and at frequencies up to ~800 Hz. Because th measurements are a complex superposition of signals that arise from locomotion, body orientation, swallowing, respiration, cardiac activity, vocal-fold vibrations and other sources, we used frequency-domain analysis and machine learning to obtain, from human subjects during natural daily activities and exercise, real-time recordings of heart rate, respiration rate, energy intensity and other essential vital signs, as well as talking time and cadence, swallow counts and patterns, and other unconventional biomarkers. We also used the device in sleep laboratories, and validated the measurements via polysomnography. 2019-11-25 2020-02 /pmc/articles/PMC7035153/ /pubmed/31768002 http://dx.doi.org/10.1038/s41551-019-0480-6 Text en Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms Reprints and permissions information is available at www.nature.com/reprints (http://www.nature.com/reprints) .
spellingShingle Article
Lee, KunHyuck
Ni, Xiaoyue
Lee, Jong Yoon
Arafa, Hany
Pe, David J.
Xu, Shuai
Avila, Raudel
Irie, Masahiro
Lee, Joo Hee
Easterlin, Ryder L
Kim, Dong Hyun
Chung, Ha Uk
Olabisi, Omolara O
Getaneh, Selam
Chung, Esther
Hill, Marc
Bell, Jeremy
Jang, Hokyung
Liu, Claire
Park, Jun Bin
Kim, Jungwoo
Kim, Sung Bong
Mehta, Sunita
Pharr, Matt
Tzavelis, Andreas
Reeder, Jonathan T.
Huang, Ivy
Deng, Yujun
Xie, Zhaoqian
Davies, Charles R.
Huang, Yonggang
Rogers, John A.
Mechanoacoustic sensing of physiological processes and body motions via a soft wireless device placed at the suprasternal notch
title Mechanoacoustic sensing of physiological processes and body motions via a soft wireless device placed at the suprasternal notch
title_full Mechanoacoustic sensing of physiological processes and body motions via a soft wireless device placed at the suprasternal notch
title_fullStr Mechanoacoustic sensing of physiological processes and body motions via a soft wireless device placed at the suprasternal notch
title_full_unstemmed Mechanoacoustic sensing of physiological processes and body motions via a soft wireless device placed at the suprasternal notch
title_short Mechanoacoustic sensing of physiological processes and body motions via a soft wireless device placed at the suprasternal notch
title_sort mechanoacoustic sensing of physiological processes and body motions via a soft wireless device placed at the suprasternal notch
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035153/
https://www.ncbi.nlm.nih.gov/pubmed/31768002
http://dx.doi.org/10.1038/s41551-019-0480-6
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