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Mechanoacoustic sensing of physiological processes and body motions via a soft wireless device placed at the suprasternal notch
Skin-mounted soft electronics incorporating high-bandwidth triaxial accelerometers can provide broad classes of physiologically relevant information, such as mechanoacoustic signatures of underlying body processes (such as those captured by a stethoscope) and precision kinematics of core body motion...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035153/ https://www.ncbi.nlm.nih.gov/pubmed/31768002 http://dx.doi.org/10.1038/s41551-019-0480-6 |
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author | Lee, KunHyuck Ni, Xiaoyue Lee, Jong Yoon Arafa, Hany Pe, David J. Xu, Shuai Avila, Raudel Irie, Masahiro Lee, Joo Hee Easterlin, Ryder L Kim, Dong Hyun Chung, Ha Uk Olabisi, Omolara O Getaneh, Selam Chung, Esther Hill, Marc Bell, Jeremy Jang, Hokyung Liu, Claire Park, Jun Bin Kim, Jungwoo Kim, Sung Bong Mehta, Sunita Pharr, Matt Tzavelis, Andreas Reeder, Jonathan T. Huang, Ivy Deng, Yujun Xie, Zhaoqian Davies, Charles R. Huang, Yonggang Rogers, John A. |
author_facet | Lee, KunHyuck Ni, Xiaoyue Lee, Jong Yoon Arafa, Hany Pe, David J. Xu, Shuai Avila, Raudel Irie, Masahiro Lee, Joo Hee Easterlin, Ryder L Kim, Dong Hyun Chung, Ha Uk Olabisi, Omolara O Getaneh, Selam Chung, Esther Hill, Marc Bell, Jeremy Jang, Hokyung Liu, Claire Park, Jun Bin Kim, Jungwoo Kim, Sung Bong Mehta, Sunita Pharr, Matt Tzavelis, Andreas Reeder, Jonathan T. Huang, Ivy Deng, Yujun Xie, Zhaoqian Davies, Charles R. Huang, Yonggang Rogers, John A. |
author_sort | Lee, KunHyuck |
collection | PubMed |
description | Skin-mounted soft electronics incorporating high-bandwidth triaxial accelerometers can provide broad classes of physiologically relevant information, such as mechanoacoustic signatures of underlying body processes (such as those captured by a stethoscope) and precision kinematics of core body motions. Here, we describe a wireless device designed to be conformally placed on the suprasternal notch for the continuous measurement of mechanoacoustic signals, from subtle vibrations of the skin at accelerations of ~10(−3) m·s(−2) to large motions of the entire body at ~10 m·s(−2), and at frequencies up to ~800 Hz. Because th measurements are a complex superposition of signals that arise from locomotion, body orientation, swallowing, respiration, cardiac activity, vocal-fold vibrations and other sources, we used frequency-domain analysis and machine learning to obtain, from human subjects during natural daily activities and exercise, real-time recordings of heart rate, respiration rate, energy intensity and other essential vital signs, as well as talking time and cadence, swallow counts and patterns, and other unconventional biomarkers. We also used the device in sleep laboratories, and validated the measurements via polysomnography. |
format | Online Article Text |
id | pubmed-7035153 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
record_format | MEDLINE/PubMed |
spelling | pubmed-70351532020-05-25 Mechanoacoustic sensing of physiological processes and body motions via a soft wireless device placed at the suprasternal notch Lee, KunHyuck Ni, Xiaoyue Lee, Jong Yoon Arafa, Hany Pe, David J. Xu, Shuai Avila, Raudel Irie, Masahiro Lee, Joo Hee Easterlin, Ryder L Kim, Dong Hyun Chung, Ha Uk Olabisi, Omolara O Getaneh, Selam Chung, Esther Hill, Marc Bell, Jeremy Jang, Hokyung Liu, Claire Park, Jun Bin Kim, Jungwoo Kim, Sung Bong Mehta, Sunita Pharr, Matt Tzavelis, Andreas Reeder, Jonathan T. Huang, Ivy Deng, Yujun Xie, Zhaoqian Davies, Charles R. Huang, Yonggang Rogers, John A. Nat Biomed Eng Article Skin-mounted soft electronics incorporating high-bandwidth triaxial accelerometers can provide broad classes of physiologically relevant information, such as mechanoacoustic signatures of underlying body processes (such as those captured by a stethoscope) and precision kinematics of core body motions. Here, we describe a wireless device designed to be conformally placed on the suprasternal notch for the continuous measurement of mechanoacoustic signals, from subtle vibrations of the skin at accelerations of ~10(−3) m·s(−2) to large motions of the entire body at ~10 m·s(−2), and at frequencies up to ~800 Hz. Because th measurements are a complex superposition of signals that arise from locomotion, body orientation, swallowing, respiration, cardiac activity, vocal-fold vibrations and other sources, we used frequency-domain analysis and machine learning to obtain, from human subjects during natural daily activities and exercise, real-time recordings of heart rate, respiration rate, energy intensity and other essential vital signs, as well as talking time and cadence, swallow counts and patterns, and other unconventional biomarkers. We also used the device in sleep laboratories, and validated the measurements via polysomnography. 2019-11-25 2020-02 /pmc/articles/PMC7035153/ /pubmed/31768002 http://dx.doi.org/10.1038/s41551-019-0480-6 Text en Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms Reprints and permissions information is available at www.nature.com/reprints (http://www.nature.com/reprints) . |
spellingShingle | Article Lee, KunHyuck Ni, Xiaoyue Lee, Jong Yoon Arafa, Hany Pe, David J. Xu, Shuai Avila, Raudel Irie, Masahiro Lee, Joo Hee Easterlin, Ryder L Kim, Dong Hyun Chung, Ha Uk Olabisi, Omolara O Getaneh, Selam Chung, Esther Hill, Marc Bell, Jeremy Jang, Hokyung Liu, Claire Park, Jun Bin Kim, Jungwoo Kim, Sung Bong Mehta, Sunita Pharr, Matt Tzavelis, Andreas Reeder, Jonathan T. Huang, Ivy Deng, Yujun Xie, Zhaoqian Davies, Charles R. Huang, Yonggang Rogers, John A. Mechanoacoustic sensing of physiological processes and body motions via a soft wireless device placed at the suprasternal notch |
title | Mechanoacoustic sensing of physiological processes and body motions via a soft wireless device placed at the suprasternal notch |
title_full | Mechanoacoustic sensing of physiological processes and body motions via a soft wireless device placed at the suprasternal notch |
title_fullStr | Mechanoacoustic sensing of physiological processes and body motions via a soft wireless device placed at the suprasternal notch |
title_full_unstemmed | Mechanoacoustic sensing of physiological processes and body motions via a soft wireless device placed at the suprasternal notch |
title_short | Mechanoacoustic sensing of physiological processes and body motions via a soft wireless device placed at the suprasternal notch |
title_sort | mechanoacoustic sensing of physiological processes and body motions via a soft wireless device placed at the suprasternal notch |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035153/ https://www.ncbi.nlm.nih.gov/pubmed/31768002 http://dx.doi.org/10.1038/s41551-019-0480-6 |
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