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The type 1 diabetes candidate gene Dexi does not affect disease risk in the nonobese diabetic mouse model

Genome wide association studies have implicated more than 50 genomic regions in type 1 diabetes (T1D). A T1D region at chromosome 16p13.13 includes the candidate genes CLEC16A and DEXI. Conclusive evidence as to which gene is causal for the disease-association of this region is missing. We previousl...

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Detalles Bibliográficos
Autores principales: Nieves-Bonilla, Janice M., Kiaf, Badr, Schuster, Cornelia, Kissler, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035193/
https://www.ncbi.nlm.nih.gov/pubmed/31435002
http://dx.doi.org/10.1038/s41435-019-0083-y