Food Effect on a Single High Dose of Carotegrast Methyl, an Oral Antagonist of α4-Integrin, in Healthy Male Subjects: A Randomised, Placebo-Controlled, Double-Blind Study

BACKGROUND AND OBJECTIVES: Carotegrast methyl, a novel prodrug, oral antagonist of α4-integrin, is in development for the treatment of active ulcerative colitis. This randomised, placebo-controlled, double-blind, crossover study evaluated the effect of food on the pharmacokinetics and pharmacodynami...

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Detalles Bibliográficos
Autores principales: Fukase, Hiroyuki, Kajioka, Toshifumi, Oikawa, Ichiro, Ikeda, Naoki, Furuie, Hidetoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035301/
https://www.ncbi.nlm.nih.gov/pubmed/31965548
http://dx.doi.org/10.1007/s40261-019-00879-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035301/
https://www.ncbi.nlm.nih.gov/pubmed/31965548
http://dx.doi.org/10.1007/s40261-019-00879-1

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