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CCN1 promotes hepatic steatosis and inflammation in non-alcoholic steatohepatitis

Non-alcoholic fatty liver disease (NAFLD) is characterized by increased uptake and accumulation of lipids in hepatocytes. Simple steatosis may progress to non-alcoholic steatohepatitis (NASH) with inflammation, hepatocellular injury and fibrosis. CCN1 is an important matrix protein that regulates ce...

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Detalles Bibliográficos
Autores principales: Ju, Linling, Sun, Yan, Xue, Hong, Chen, Lin, Gu, Chunyan, Shao, Jianguo, Lu, Rujian, Luo, Xi, Wei, Jue, Ma, Xiong, Bian, Zhaolian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035350/
https://www.ncbi.nlm.nih.gov/pubmed/32081971
http://dx.doi.org/10.1038/s41598-020-60138-8