Light-induced silencing of neural activity in Rosa26 knock-in and BAC transgenic mice conditionally expressing the microbial halorhodopsin eNpHR3

An engineered light-inducible chloride pump, Natronomonas pharaonis halorhodopsin 3 (eNpHR3) enables temporally and spatially precise inhibition of genetically defined cell populations in the intact nervous tissues. In this report, we show the generation of new mouse strains that express eNpHR3-EYFP...

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Detalles Bibliográficos
Autores principales: Imayoshi, Itaru, Tabuchi, Sawako, Matsumoto, Mami, Kitano, Satsuki, Miyachi, Hitoshi, Kageyama, Ryoichiro, Yamanaka, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035371/
https://www.ncbi.nlm.nih.gov/pubmed/32081938
http://dx.doi.org/10.1038/s41598-020-59984-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035371/
https://www.ncbi.nlm.nih.gov/pubmed/32081938
http://dx.doi.org/10.1038/s41598-020-59984-3

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