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Trauma Induced Calcium Pyrophosphate Deposition Disease of the Lumbar Spine

Inflammatory arthritis, such as pseudogout or otherwise referred to as calcium pyrophosphate (CPP) crystal arthritis or calcium pyrophosphate deposition (CPPD) disease, is characterized by the deposition of crystal formation and deposition in large joints. CPPD is known to affect the elderly populat...

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Autores principales: Greca, Indrit, Ben Gabr, Jihad, Perl, Andras, Bryant, Stephanie, Zaccarini, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035534/
https://www.ncbi.nlm.nih.gov/pubmed/32095306
http://dx.doi.org/10.1155/2020/3218350
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author Greca, Indrit
Ben Gabr, Jihad
Perl, Andras
Bryant, Stephanie
Zaccarini, Dan
author_facet Greca, Indrit
Ben Gabr, Jihad
Perl, Andras
Bryant, Stephanie
Zaccarini, Dan
author_sort Greca, Indrit
collection PubMed
description Inflammatory arthritis, such as pseudogout or otherwise referred to as calcium pyrophosphate (CPP) crystal arthritis or calcium pyrophosphate deposition (CPPD) disease, is characterized by the deposition of crystal formation and deposition in large joints. CPPD is known to affect the elderly population and commonly manifests as inflammation of knees, hips, and shoulders. CPPD disease involving the spine has been infrequently encountered in practice and rarely described in the literature. Here, we describe a case of an 80-year-old female with no known history of inflammatory arthritis who presented with left lower extremity weakness and fall, initially thought to have discitis, later confirming CPPD of the spine through biopsy and ultimately resolution of symptoms with anti-inflammatory agents. Although consisting of different clinical presentations, two other case reports have described CPPD of the spine with similar radiographic findings, to this author's knowledge. With the radiologic similarities, this unique case serves to raise awareness in the medical community and possibly place pseudogout of the spine on the differential list when such cases are encountered. As a result, patients can be initiated on benign anti-inflammatory agents, avoiding invasive testing and unnecessary antibiotic exposure.
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spelling pubmed-70355342020-02-24 Trauma Induced Calcium Pyrophosphate Deposition Disease of the Lumbar Spine Greca, Indrit Ben Gabr, Jihad Perl, Andras Bryant, Stephanie Zaccarini, Dan Case Rep Rheumatol Case Report Inflammatory arthritis, such as pseudogout or otherwise referred to as calcium pyrophosphate (CPP) crystal arthritis or calcium pyrophosphate deposition (CPPD) disease, is characterized by the deposition of crystal formation and deposition in large joints. CPPD is known to affect the elderly population and commonly manifests as inflammation of knees, hips, and shoulders. CPPD disease involving the spine has been infrequently encountered in practice and rarely described in the literature. Here, we describe a case of an 80-year-old female with no known history of inflammatory arthritis who presented with left lower extremity weakness and fall, initially thought to have discitis, later confirming CPPD of the spine through biopsy and ultimately resolution of symptoms with anti-inflammatory agents. Although consisting of different clinical presentations, two other case reports have described CPPD of the spine with similar radiographic findings, to this author's knowledge. With the radiologic similarities, this unique case serves to raise awareness in the medical community and possibly place pseudogout of the spine on the differential list when such cases are encountered. As a result, patients can be initiated on benign anti-inflammatory agents, avoiding invasive testing and unnecessary antibiotic exposure. Hindawi 2020-02-10 /pmc/articles/PMC7035534/ /pubmed/32095306 http://dx.doi.org/10.1155/2020/3218350 Text en Copyright © 2020 Indrit Greca et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Greca, Indrit
Ben Gabr, Jihad
Perl, Andras
Bryant, Stephanie
Zaccarini, Dan
Trauma Induced Calcium Pyrophosphate Deposition Disease of the Lumbar Spine
title Trauma Induced Calcium Pyrophosphate Deposition Disease of the Lumbar Spine
title_full Trauma Induced Calcium Pyrophosphate Deposition Disease of the Lumbar Spine
title_fullStr Trauma Induced Calcium Pyrophosphate Deposition Disease of the Lumbar Spine
title_full_unstemmed Trauma Induced Calcium Pyrophosphate Deposition Disease of the Lumbar Spine
title_short Trauma Induced Calcium Pyrophosphate Deposition Disease of the Lumbar Spine
title_sort trauma induced calcium pyrophosphate deposition disease of the lumbar spine
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035534/
https://www.ncbi.nlm.nih.gov/pubmed/32095306
http://dx.doi.org/10.1155/2020/3218350
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