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Metformin Reduces the Senescence of Renal Tubular Epithelial Cells in Diabetic Nephropathy via the MBNL1/miR-130a-3p/STAT3 Pathway

Senescence of renal tubular epithelial cells plays an important role in diabetic nephropathy, but the mechanism is unknown. Metformin may alleviate diabetic nephropathy by reducing this senescence. This study is aimed at clarifying the effects and mechanism of metformin on the senescence of renal tu...

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Detalles Bibliográficos
Autores principales: Jiang, Xue, Ruan, Xue-lei, Xue, Yi-xue, Yang, Shuang, Shi, Mai, Wang, Li-ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035567/
https://www.ncbi.nlm.nih.gov/pubmed/32104542
http://dx.doi.org/10.1155/2020/8708236