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Defective HIV-1 proviruses produce viral proteins

HIV-1 proviruses persist in the CD4(+) T cells of HIV-infected individuals despite years of combination antiretroviral therapy (cART) with suppression of HIV-1 RNA levels <40 copies/mL. Greater than 95% of these proviruses detected in circulating peripheral blood mononuclear cells (PBMCs) are ref...

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Detalles Bibliográficos
Autores principales:	Imamichi, Hiromi, Smith, Mindy, Adelsberger, Joseph W., Izumi, Taisuke, Scrimieri, Francesca, Sherman, Brad T., Rehm, Catherine A., Imamichi, Tomozumi, Pau, Alice, Catalfamo, Marta, Fauci, Anthony S., Lane, H. Clifford
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2020
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035625/ https://www.ncbi.nlm.nih.gov/pubmed/32029589 http://dx.doi.org/10.1073/pnas.1917876117

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