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Comparative analysis of ChIP-exo peak-callers: impact of data quality, read duplication and binding subtypes
BACKGROUND: ChIP (Chromatin immunoprecipitation)-exo has emerged as an important and versatile improvement over conventional ChIP-seq as it reduces the level of noise, maps the transcription factor (TF) binding location in a very precise manner, upto single base-pair resolution, and enables binding...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035708/ https://www.ncbi.nlm.nih.gov/pubmed/32085702 http://dx.doi.org/10.1186/s12859-020-3403-3 |