Histone H3K27 acetylation is dispensable for enhancer activity in mouse embryonic stem cells

H3K27ac is well recognized as a marker for active enhancers and a great indicator of enhancer activity. However, its functional impact on transcription has not been characterized. By substituting lysine 27 in histone variant H3.3 with arginine in mouse embryonic stem cells, we diminish the vast majo...

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Detalles Bibliográficos
Autores principales: Zhang, Tiantian, Zhang, Zhuqiang, Dong, Qiang, Xiong, Jun, Zhu, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035716/
https://www.ncbi.nlm.nih.gov/pubmed/32085783
http://dx.doi.org/10.1186/s13059-020-01957-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035716/
https://www.ncbi.nlm.nih.gov/pubmed/32085783
http://dx.doi.org/10.1186/s13059-020-01957-w

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