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Mutant dlx3b disturbs normal tooth mineralization and bone formation in zebrafish

BACKGROUND: Tricho-dento-osseous (TDO) syndrome is an autosomal dominant disorder characterized by anomalies in hair, teeth and bone (OMIM190320). Various mutations of Distal-Less 3 (DLX3) gene are found to be responsible for human TDO. The aim of this study was to investigate effects of DLX3 on too...

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Detalles Bibliográficos
Autores principales: Pang, Liping, Zhang, Zhichun, Shen, Yan, Cheng, Zhenchao, Gao, Xuejun, Zhang, Bo, Wang, Xiaoyan, Tian, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035872/
https://www.ncbi.nlm.nih.gov/pubmed/32117623
http://dx.doi.org/10.7717/peerj.8515

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