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Activated Hepatic Stellate Cells (HSCs) Exert Immunosuppressive Effects in Hepatocellular Carcinoma by Producing Complement C3

OBJECTIVE: Hepatic stellate cells (HSCs) are the important players in liver cirrhosis and liver cancer. They also act as critical mediators of immunosuppression in hepatocellular carcinoma (HCC). In this study, we hypothesized that HSCs promote HCC progression via C3. METHODS: C3 in HSCs was knocked...

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Detalles Bibliográficos
Autores principales:	Xu, Yaping, Huang, Yihao, Xu, Wanqiong, Zheng, Xiaohui, Yi, Xue, Huang, Liyue, Wang, Yuxiao, Wu, Kangni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035898/ https://www.ncbi.nlm.nih.gov/pubmed/32110047 http://dx.doi.org/10.2147/OTT.S234920

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