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Review of Testicular Tumor: Diagnostic Approach and Management Outcome in Africa

Testicular cancer is a common malignancy in young males with higher incidence in developed nations but with the lowest incidence in Africa (0.3–0.6/100 000). Ironically, the global testicular cancer mortality rate has shown a reverse trend to its incidence with higher rates in low- and middle-income...

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Detalles Bibliográficos
Autores principales: Cassell, Ayun, Jalloh, Mohamed, Ndoye, Medina, Yunusa, Bashir, Mbodji, Mouhamadou, Diallo, Abdourahmane, Gaye, Omar, Labou, Issa, Niang, Lamine, Gueye, Serigne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035899/
https://www.ncbi.nlm.nih.gov/pubmed/32110551
http://dx.doi.org/10.2147/RRU.S242398
Descripción
Sumario:Testicular cancer is a common malignancy in young males with higher incidence in developed nations but with the lowest incidence in Africa (0.3–0.6/100 000). Ironically, the global testicular cancer mortality rate has shown a reverse trend to its incidence with higher rates in low- and middle-income countries (0.5 per 100 000) than in high-income countries. Data from GLOBOCAN 2008 have shown relatively high mortality rates in sub-Saharan countries like Mali, Ethiopia, Niger and Malawi. The prognosis of testicular tumor is good with remarkable chemosensitivity to cisplatin-based regimen. Early diagnosis, careful staging and a multidisciplinary management approach is crucial to achieve this optimal result. These results are achievable in the sub-Saharan region if the relevant resources are appropriated for cancer care and clinical guidelines are formulated in a regional context.