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Review of Testicular Tumor: Diagnostic Approach and Management Outcome in Africa

Testicular cancer is a common malignancy in young males with higher incidence in developed nations but with the lowest incidence in Africa (0.3–0.6/100 000). Ironically, the global testicular cancer mortality rate has shown a reverse trend to its incidence with higher rates in low- and middle-income...

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Autores principales: Cassell, Ayun, Jalloh, Mohamed, Ndoye, Medina, Yunusa, Bashir, Mbodji, Mouhamadou, Diallo, Abdourahmane, Gaye, Omar, Labou, Issa, Niang, Lamine, Gueye, Serigne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035899/
https://www.ncbi.nlm.nih.gov/pubmed/32110551
http://dx.doi.org/10.2147/RRU.S242398
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author Cassell, Ayun
Jalloh, Mohamed
Ndoye, Medina
Yunusa, Bashir
Mbodji, Mouhamadou
Diallo, Abdourahmane
Gaye, Omar
Labou, Issa
Niang, Lamine
Gueye, Serigne
author_facet Cassell, Ayun
Jalloh, Mohamed
Ndoye, Medina
Yunusa, Bashir
Mbodji, Mouhamadou
Diallo, Abdourahmane
Gaye, Omar
Labou, Issa
Niang, Lamine
Gueye, Serigne
author_sort Cassell, Ayun
collection PubMed
description Testicular cancer is a common malignancy in young males with higher incidence in developed nations but with the lowest incidence in Africa (0.3–0.6/100 000). Ironically, the global testicular cancer mortality rate has shown a reverse trend to its incidence with higher rates in low- and middle-income countries (0.5 per 100 000) than in high-income countries. Data from GLOBOCAN 2008 have shown relatively high mortality rates in sub-Saharan countries like Mali, Ethiopia, Niger and Malawi. The prognosis of testicular tumor is good with remarkable chemosensitivity to cisplatin-based regimen. Early diagnosis, careful staging and a multidisciplinary management approach is crucial to achieve this optimal result. These results are achievable in the sub-Saharan region if the relevant resources are appropriated for cancer care and clinical guidelines are formulated in a regional context.
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spelling pubmed-70358992020-02-27 Review of Testicular Tumor: Diagnostic Approach and Management Outcome in Africa Cassell, Ayun Jalloh, Mohamed Ndoye, Medina Yunusa, Bashir Mbodji, Mouhamadou Diallo, Abdourahmane Gaye, Omar Labou, Issa Niang, Lamine Gueye, Serigne Res Rep Urol Review Testicular cancer is a common malignancy in young males with higher incidence in developed nations but with the lowest incidence in Africa (0.3–0.6/100 000). Ironically, the global testicular cancer mortality rate has shown a reverse trend to its incidence with higher rates in low- and middle-income countries (0.5 per 100 000) than in high-income countries. Data from GLOBOCAN 2008 have shown relatively high mortality rates in sub-Saharan countries like Mali, Ethiopia, Niger and Malawi. The prognosis of testicular tumor is good with remarkable chemosensitivity to cisplatin-based regimen. Early diagnosis, careful staging and a multidisciplinary management approach is crucial to achieve this optimal result. These results are achievable in the sub-Saharan region if the relevant resources are appropriated for cancer care and clinical guidelines are formulated in a regional context. Dove 2020-02-18 /pmc/articles/PMC7035899/ /pubmed/32110551 http://dx.doi.org/10.2147/RRU.S242398 Text en © 2020 Cassell et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Cassell, Ayun
Jalloh, Mohamed
Ndoye, Medina
Yunusa, Bashir
Mbodji, Mouhamadou
Diallo, Abdourahmane
Gaye, Omar
Labou, Issa
Niang, Lamine
Gueye, Serigne
Review of Testicular Tumor: Diagnostic Approach and Management Outcome in Africa
title Review of Testicular Tumor: Diagnostic Approach and Management Outcome in Africa
title_full Review of Testicular Tumor: Diagnostic Approach and Management Outcome in Africa
title_fullStr Review of Testicular Tumor: Diagnostic Approach and Management Outcome in Africa
title_full_unstemmed Review of Testicular Tumor: Diagnostic Approach and Management Outcome in Africa
title_short Review of Testicular Tumor: Diagnostic Approach and Management Outcome in Africa
title_sort review of testicular tumor: diagnostic approach and management outcome in africa
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035899/
https://www.ncbi.nlm.nih.gov/pubmed/32110551
http://dx.doi.org/10.2147/RRU.S242398
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