Biased visibility in Hi-C datasets marks dynamically regulated condensed and decondensed chromatin states genome-wide

BACKGROUND: Proximity ligation based techniques, like Hi-C, involve restriction digestion followed by ligation of formaldehyde cross-linked chromatin. Distinct chromatin states can impact the restriction digestion, and hence the visibility in the contact maps, of engaged loci. Yet, the extent and th...

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Detalles Bibliográficos
Autores principales: Chandradoss, Keerthivasan Raanin, Guthikonda, Prashanth Kumar, Kethavath, Srinivas, Dass, Monika, Singh, Harpreet, Nayak, Rakhee, Kurukuti, Sreenivasulu, Sandhu, Kuljeet Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036197/
https://www.ncbi.nlm.nih.gov/pubmed/32087673
http://dx.doi.org/10.1186/s12864-020-6580-6

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