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Unphosphorylated STAT3 in heterochromatin formation and tumor suppression in lung cancer

BACKGROUND: Aberrant JAK/STAT activation has been detected in many types of human cancers. The role of JAK/STAT activation in cancer has been mostly attributed to direct transcriptional regulation of target genes by phosphorylated STAT (pSTAT), while the unphosphorylated STAT (uSTAT) is believed to...

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Detalles Bibliográficos
Autores principales:	Dutta, Pranabananda, Zhang, Lin, Zhang, Huijun, Peng, Qin, Montgrain, Phillippe R., Wang, Yingxiao, Song, Yuanlin, Li, Jinghong, Li, Willis X.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036253/ https://www.ncbi.nlm.nih.gov/pubmed/32087696 http://dx.doi.org/10.1186/s12885-020-6649-2

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