Virus Isolation from the First Patient with SARS-CoV-2 in Korea

Novel coronavirus (SARS-CoV-2) is found to cause a large outbreak started from Wuhan since December 2019 in China and SARS-CoV-2 infections have been reported with epidemiological linkage to China in 25 countries until now. We isolated SARS-CoV-2 from the oropharyngeal sample obtained from the patie...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Wan Beom, Kwon, Nak-Jung, Choi, Su-Jin, Kang, Chang Kyung, Choe, Pyoeng Gyun, Kim, Jin Yong, Yun, Jiyoung, Lee, Gir-Won, Seong, Moon-Woo, Kim, Nam Joong, Seo, Jeong-Sun, Oh, Myoung-don
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2020
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036342/
https://www.ncbi.nlm.nih.gov/pubmed/32080990
http://dx.doi.org/10.3346/jkms.2020.35.e84
Descripción
Sumario:Novel coronavirus (SARS-CoV-2) is found to cause a large outbreak started from Wuhan since December 2019 in China and SARS-CoV-2 infections have been reported with epidemiological linkage to China in 25 countries until now. We isolated SARS-CoV-2 from the oropharyngeal sample obtained from the patient with the first laboratory-confirmed SARS-CoV-2 infection in Korea. Cytopathic effects of SARS-CoV-2 in the Vero cell cultures were confluent 3 days after the first blind passage of the sample. Coronavirus was confirmed with spherical particle having a fringe reminiscent of crown on transmission electron microscopy. Phylogenetic analyses of whole genome sequences showed that it clustered with other SARS-CoV-2 reported from Wuhan.

Ejemplares similares