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Complete remission with immunotherapy: Case report of a patient with metastatic bladder cancer to the humerus

Bladder cancer is the sixth most common malignancy in the United States. Cisplatin combination regimens are first line therapy for patients with metastatic urothelial bladder cancer who are eligible candidates and no treatments have shown to improve outcome compared to chemotherapy for the past 20 y...

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Detalles Bibliográficos
Autores principales: Abdelhakam, D., Young, P.R., Jain, M.K., Nassar, A., Copland, J.A., Tan, W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036445/
https://www.ncbi.nlm.nih.gov/pubmed/32123665
http://dx.doi.org/10.1016/j.eucr.2020.101130
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author Abdelhakam, D.
Young, P.R.
Jain, M.K.
Nassar, A.
Copland, J.A.
Tan, W.
author_facet Abdelhakam, D.
Young, P.R.
Jain, M.K.
Nassar, A.
Copland, J.A.
Tan, W.
author_sort Abdelhakam, D.
collection PubMed
description Bladder cancer is the sixth most common malignancy in the United States. Cisplatin combination regimens are first line therapy for patients with metastatic urothelial bladder cancer who are eligible candidates and no treatments have shown to improve outcome compared to chemotherapy for the past 20 years. Significant advances were made in past 2–3 years and the most significant was the introduction of checkpoints inhibitors in bladder cancer treatment. We present a patient diagnosed with metastatic urothelial carcinoma who progressed while on cisplatin/gemcitabine chemotherapy in the form of oligometastasis to the bone. He has achieved a durable complete response with atezolizumab.
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spelling pubmed-70364452020-03-02 Complete remission with immunotherapy: Case report of a patient with metastatic bladder cancer to the humerus Abdelhakam, D. Young, P.R. Jain, M.K. Nassar, A. Copland, J.A. Tan, W. Urol Case Rep Oncology Bladder cancer is the sixth most common malignancy in the United States. Cisplatin combination regimens are first line therapy for patients with metastatic urothelial bladder cancer who are eligible candidates and no treatments have shown to improve outcome compared to chemotherapy for the past 20 years. Significant advances were made in past 2–3 years and the most significant was the introduction of checkpoints inhibitors in bladder cancer treatment. We present a patient diagnosed with metastatic urothelial carcinoma who progressed while on cisplatin/gemcitabine chemotherapy in the form of oligometastasis to the bone. He has achieved a durable complete response with atezolizumab. Elsevier 2020-02-12 /pmc/articles/PMC7036445/ /pubmed/32123665 http://dx.doi.org/10.1016/j.eucr.2020.101130 Text en © 2020 Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Oncology
Abdelhakam, D.
Young, P.R.
Jain, M.K.
Nassar, A.
Copland, J.A.
Tan, W.
Complete remission with immunotherapy: Case report of a patient with metastatic bladder cancer to the humerus
title Complete remission with immunotherapy: Case report of a patient with metastatic bladder cancer to the humerus
title_full Complete remission with immunotherapy: Case report of a patient with metastatic bladder cancer to the humerus
title_fullStr Complete remission with immunotherapy: Case report of a patient with metastatic bladder cancer to the humerus
title_full_unstemmed Complete remission with immunotherapy: Case report of a patient with metastatic bladder cancer to the humerus
title_short Complete remission with immunotherapy: Case report of a patient with metastatic bladder cancer to the humerus
title_sort complete remission with immunotherapy: case report of a patient with metastatic bladder cancer to the humerus
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036445/
https://www.ncbi.nlm.nih.gov/pubmed/32123665
http://dx.doi.org/10.1016/j.eucr.2020.101130
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