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Complete remission with immunotherapy: Case report of a patient with metastatic bladder cancer to the humerus
Bladder cancer is the sixth most common malignancy in the United States. Cisplatin combination regimens are first line therapy for patients with metastatic urothelial bladder cancer who are eligible candidates and no treatments have shown to improve outcome compared to chemotherapy for the past 20 y...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036445/ https://www.ncbi.nlm.nih.gov/pubmed/32123665 http://dx.doi.org/10.1016/j.eucr.2020.101130 |
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author | Abdelhakam, D. Young, P.R. Jain, M.K. Nassar, A. Copland, J.A. Tan, W. |
author_facet | Abdelhakam, D. Young, P.R. Jain, M.K. Nassar, A. Copland, J.A. Tan, W. |
author_sort | Abdelhakam, D. |
collection | PubMed |
description | Bladder cancer is the sixth most common malignancy in the United States. Cisplatin combination regimens are first line therapy for patients with metastatic urothelial bladder cancer who are eligible candidates and no treatments have shown to improve outcome compared to chemotherapy for the past 20 years. Significant advances were made in past 2–3 years and the most significant was the introduction of checkpoints inhibitors in bladder cancer treatment. We present a patient diagnosed with metastatic urothelial carcinoma who progressed while on cisplatin/gemcitabine chemotherapy in the form of oligometastasis to the bone. He has achieved a durable complete response with atezolizumab. |
format | Online Article Text |
id | pubmed-7036445 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-70364452020-03-02 Complete remission with immunotherapy: Case report of a patient with metastatic bladder cancer to the humerus Abdelhakam, D. Young, P.R. Jain, M.K. Nassar, A. Copland, J.A. Tan, W. Urol Case Rep Oncology Bladder cancer is the sixth most common malignancy in the United States. Cisplatin combination regimens are first line therapy for patients with metastatic urothelial bladder cancer who are eligible candidates and no treatments have shown to improve outcome compared to chemotherapy for the past 20 years. Significant advances were made in past 2–3 years and the most significant was the introduction of checkpoints inhibitors in bladder cancer treatment. We present a patient diagnosed with metastatic urothelial carcinoma who progressed while on cisplatin/gemcitabine chemotherapy in the form of oligometastasis to the bone. He has achieved a durable complete response with atezolizumab. Elsevier 2020-02-12 /pmc/articles/PMC7036445/ /pubmed/32123665 http://dx.doi.org/10.1016/j.eucr.2020.101130 Text en © 2020 Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Oncology Abdelhakam, D. Young, P.R. Jain, M.K. Nassar, A. Copland, J.A. Tan, W. Complete remission with immunotherapy: Case report of a patient with metastatic bladder cancer to the humerus |
title | Complete remission with immunotherapy: Case report of a patient with metastatic bladder cancer to the humerus |
title_full | Complete remission with immunotherapy: Case report of a patient with metastatic bladder cancer to the humerus |
title_fullStr | Complete remission with immunotherapy: Case report of a patient with metastatic bladder cancer to the humerus |
title_full_unstemmed | Complete remission with immunotherapy: Case report of a patient with metastatic bladder cancer to the humerus |
title_short | Complete remission with immunotherapy: Case report of a patient with metastatic bladder cancer to the humerus |
title_sort | complete remission with immunotherapy: case report of a patient with metastatic bladder cancer to the humerus |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036445/ https://www.ncbi.nlm.nih.gov/pubmed/32123665 http://dx.doi.org/10.1016/j.eucr.2020.101130 |
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