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ISX-9 manipulates endocrine progenitor fate revealing conserved intestinal lineages in mouse and human organoids
OBJECTIVE: Enteroendocrine cells (EECs) survey the gut luminal environment and coordinate hormonal, immune and neuronal responses to it. They exhibit well-characterised physiological roles ranging from the control of local gut function to whole body metabolism, but little is known regarding the regu...
Autores principales: | Tsakmaki, Anastasia, Fonseca Pedro, Patricia, Pavlidis, Polychronis, Hayee, Bu’Hussain, Bewick, Gavin A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036449/ https://www.ncbi.nlm.nih.gov/pubmed/32180555 http://dx.doi.org/10.1016/j.molmet.2020.01.012 |
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