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Characterization of HIV-1 Integrase Gene and Resistance Associated Mutations Prior to Roll out of Integrase Inhibitors by Kenyan National HIV-Treatment Program in Kenya

BACKGROUND: Antiretroviral therapy containing an integrase strand transfer inhibitor plus two Nucleoside Reverse Transcriptase inhibitors has now been recommended for treatment of HIV-1-infected patients. This thus determined possible pre-existing integrase resistance-associated mutations in the int...

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Detalles Bibliográficos
Autores principales: Mabeya, Sepha, Nyamache, Anthony, Ngugi, Caroline, Nyerere, Andrew, Lihana, Raphael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research and Publications Office of Jimma University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036466/
https://www.ncbi.nlm.nih.gov/pubmed/32116431
http://dx.doi.org/10.4314/ejhs.v30i1.6