Analysis of Flagellin-Specific Adaptive Immunity Reveals Links to Dysbiosis in Patients With Inflammatory Bowel Disease

BACKGROUND & AIMS: Bacterial flagellin is an important antigen in inflammatory bowel disease, but the role of flagellin-specific CD4(+) T cells in disease pathogenesis remains unclear. Also unknown is how changes in intestinal microbiome intersect with those in microbiota-specific CD4(+) T cells...

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Detalles Bibliográficos
Autores principales: Cook, Laura, Lisko, Daniel J., Wong, May Q., Garcia, Rosa V., Himmel, Megan E., Seidman, Ernest G., Bressler, Brian, Levings, Megan K., Steiner, Theodore S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036547/
https://www.ncbi.nlm.nih.gov/pubmed/31790809
http://dx.doi.org/10.1016/j.jcmgh.2019.11.012

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