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Mu and Delta Opioid Receptors Are Coexpressed and Functionally Interact in the Enteric Nervous System of the Mouse Colon
BACKGROUND & AIMS: Functional interactions between the mu opioid receptor (MOR) and delta opioid receptor (DOR) represent a potential target for novel analgesics and may drive the effects of the clinically approved drug eluxadoline for the treatment of diarrhea-predominant irritable bowel syndro...
Autores principales: | DiCello, Jesse J., Carbone, Simona E., Saito, Ayame, Rajasekhar, Pradeep, Ceredig, Rhian A., Pham, Vi, Valant, Celine, Christopoulos, Arthur, Veldhuis, Nicholas A., Canals, Meritxell, Massotte, Dominique, Poole, Daniel P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036548/ https://www.ncbi.nlm.nih.gov/pubmed/31759144 http://dx.doi.org/10.1016/j.jcmgh.2019.11.006 |
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