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Human Colon-on-a-Chip Enables Continuous In Vitro Analysis of Colon Mucus Layer Accumulation and Physiology

BACKGROUND & AIMS: The mucus layer in the human colon protects against commensal bacteria and pathogens, and defects in its unique bilayered structure contribute to intestinal disorders, such as ulcerative colitis. However, our understanding of colon physiology is limited by the lack of in vitro...

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Detalles Bibliográficos
Autores principales:	Sontheimer-Phelps, Alexandra, Chou, David B., Tovaglieri, Alessio, Ferrante, Thomas C., Duckworth, Taylor, Fadel, Cicely, Frismantas, Viktoras, Sutherland, Arlene D., Jalili-Firoozinezhad, Sasan, Kasendra, Magdalena, Stas, Eric, Weaver, James C., Richmond, Camilla A., Levy, Oren, Prantil-Baun, Rachelle, Breault, David T., Ingber, Donald E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036549/ https://www.ncbi.nlm.nih.gov/pubmed/31778828 http://dx.doi.org/10.1016/j.jcmgh.2019.11.008

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