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Lipidated Analogs of the LL-37-Derived Peptide Fragment KR12—Structural Analysis, Surface-Active Properties and Antimicrobial Activity
An increasing number of multidrug-resistant pathogens is a serious problem of modern medicine and new antibiotics are highly demanded. In this study, different n-alkyl acids (C(2)-C(14)) and aromatic acids (benzoic and trans-cinnamic) were conjugated to the N-terminus of KR12 amide. The effect of th...
Autores principales: | Kamysz, Elżbieta, Sikorska, Emilia, Jaśkiewicz, Maciej, Bauer, Marta, Neubauer, Damian, Bartoszewska, Sylwia, Barańska-Rybak, Wioletta, Kamysz, Wojciech |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036753/ https://www.ncbi.nlm.nih.gov/pubmed/32019109 http://dx.doi.org/10.3390/ijms21030887 |
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