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Biological Evaluation and In Silico Study of Benzoic Acid Derivatives from Bjerkandera adusta Targeting Proteostasis Network Modules
A main cellular functional module that becomes dysfunctional during aging is the proteostasis network. In the present study, we show that benzoic acid derivatives isolated from Bjerkandera adusta promote the activity of the two main protein degradation systems, namely the ubiquitin-proteasome (UPP)...
Autores principales: | Georgousaki, Katerina, Tsafantakis, Nikolaos, Gumeni, Sentiljana, Lambrinidis, George, González-Menéndez, Victor, Tormo, Jose R., Genilloud, Olga, Trougakos, Ioannis P., Fokialakis, Nikolas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036779/ https://www.ncbi.nlm.nih.gov/pubmed/32033190 http://dx.doi.org/10.3390/molecules25030666 |
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