Cargando…

An Isolated Complex V Inefficiency and Dysregulated Mitochondrial Function in Immortalized Lymphocytes from ME/CFS Patients

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is an enigmatic condition characterized by exacerbation of symptoms after exertion (post-exertional malaise or “PEM”), and by fatigue whose severity and associated requirement for rest are excessive and disproportionate to the fatigue-induc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Missailidis, Daniel, Annesley, Sarah J., Allan, Claire Y., Sanislav, Oana, Lidbury, Brett A., Lewis, Donald P., Fisher, Paul R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036826/ https://www.ncbi.nlm.nih.gov/pubmed/32041178 http://dx.doi.org/10.3390/ijms21031074

Ejemplares similares

Dysregulated Provision of Oxidisable Substrates to the Mitochondria in ME/CFS Lymphoblasts
por: Missailidis, Daniel, et al.
Publicado: (2021)

Could the kynurenine pathway be the key missing piece of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) complex puzzle?
por: Kavyani, Bahar, et al.
Publicado: (2022)

Biomedical Insights That Inform the Diagnosis of ME/CFS
por: Lidbury, Brett A., et al.
Publicado: (2020)

Cytotoxicity and Mitochondrial Dysregulation Caused by α-Synuclein in Dictyostelium discoideum
por: Fernando, Sanjanie, et al.
Publicado: (2020)

Cell-Based Blood Biomarkers for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
por: Missailidis, Daniel, et al.
Publicado: (2020)

Immortalized Parkinson's disease lymphocytes have enhanced mitochondrial respiratory activity
por: Annesley, Sarah J., et al.
Publicado: (2016)

Dysregulated Gene Expression in Lymphoblasts from Parkinson’s Disease
por: Annesley, Sarah Jane, et al.
Publicado: (2022)

Mitochondrial HTRA2 Plays a Positive, Protective Role in Dictyostelium discoideum but Is Cytotoxic When Overexpressed
por: Chen, Suwei, et al.
Publicado: (2018)

Cytopathological Outcomes of Knocking down Expression of Mitochondrial Complex II Subunits in Dictyostelium discoideum
por: Lay, Sui, et al.
Publicado: (2022)

Rethinking ME/CFS Diagnostic Reference Intervals via Machine Learning, and the Utility of Activin B for Defining Symptom Severity
por: Lidbury, Brett A., et al.
Publicado: (2019)

Activin B is a novel biomarker for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) diagnosis: a cross sectional study
por: Lidbury, Brett A., et al.
Publicado: (2017)

Weighting of orthostatic intolerance time measurements with standing difficulty score stratifies ME/CFS symptom severity and analyte detection
por: Richardson, Alice M., et al.
Publicado: (2018)

Relationships between Mitochondrial Function, AMPK, and TORC1 Signaling in Lymphoblasts with Premutation Alleles of the FMR1 Gene
por: Fisher, Paul R., et al.
Publicado: (2021)

How Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Progresses: The Natural History of ME/CFS
por: Nacul, Luis, et al.
Publicado: (2020)

Our Evolving Understanding of ME/CFS
por: Friedman, Kenneth J., et al.
Publicado: (2021)

ME/CFS: Past, Present and Future
por: Weir, William, et al.
Publicado: (2021)

Endothelial dysfunction in ME/CFS patients
por: Sandvik, Miriam Kristine, et al.
Publicado: (2023)

Perceptions of European ME/CFS Experts Concerning Knowledge and Understanding of ME/CFS among Primary Care Physicians in Europe: A Report from the European ME/CFS Research Network (EUROMENE)
por: Cullinan, John, et al.
Publicado: (2021)

Advances in ME/CFS: Past, Present, and Future
por: Friedman, Kenneth J.
Publicado: (2019)

Three Cases of Severe ME/CFS in Adults
por: Williams, Leah R., et al.
Publicado: (2021)

Turning a Corner in ME/CFS Research
por: Pheby, Derek F. H., et al.
Publicado: (2021)

Mental health screening in adolescents with CFS/ME
por: Loades, Maria E., et al.
Publicado: (2021)

Das "Monster" ME/CFS wird greifbar
por: Stollhoff, Kirsten
Publicado: (2022)

A Conserved Role for LRRK2 and Roco Proteins in the Regulation of Mitochondrial Activity
por: Rosenbusch, Katharina E., et al.
Publicado: (2021)

A systematic review of metabolomic dysregulation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis/Systemic Exertion Intolerance Disease (CFS/ME/SEID)
por: Huth, Teilah Kathryn, et al.
Publicado: (2020)

The impact of CFS/ME on employment and productivity in the UK: a cross-sectional study based on the CFS/ME national outcomes database
por: Collin, Simon M, et al.
Publicado: (2011)

Pathological Mechanisms Underlying Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
por: Missailidis, Daniel, et al.
Publicado: (2019)

Unravelling myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): Gender‐specific changes in the microRNA expression profiling in ME/CFS
por: Cheema, Amanpreet K., et al.
Publicado: (2020)

Correction: The impact of CFS/ME on employment and productivity in the UK: a cross-sectional study based on the CFS/ME national outcomes database
por: Collin, Simon M, et al.
Publicado: (2023)

Post-Exertional Malaise Is Associated with Hypermetabolism, Hypoacetylation and Purine Metabolism Deregulation in ME/CFS Cases
por: McGregor, Neil R., et al.
Publicado: (2019)

Separating Patients with SEID from Those with CFS in the French ME/CFS Association, with Some Thoughts on Nomenclature
por: Campagne, Julien, et al.
Publicado: (2022)

The Economic impact of ME/CFS: Individual and societal costs
por: Jason, Leonard A, et al.
Publicado: (2008)

Editorial: Advances in ME/CFS Research and Clinical Care
por: Friedman, Kenneth J., et al.
Publicado: (2019)

The IDO Metabolic Trap Hypothesis for the Etiology of ME/CFS
por: Kashi, Alex A., et al.
Publicado: (2019)

Life-Threatening Malnutrition in Very Severe ME/CFS
por: Baxter, Helen, et al.
Publicado: (2021)

Extremely Severe ME/CFS—A Personal Account
por: Dafoe, Whitney
Publicado: (2021)

Editorial: Infectious and inflammatory mechanistic underpinnings of CFS/ME
por: Burton, Alexander Robert
Publicado: (2023)

Association of mitochondrial DNA variants with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) symptoms
por: Hanson, Maureen R., et al.
Publicado: (2016)

The Parkinson's disease-associated protein DJ-1 plays a positive nonmitochondrial role in endocytosis in Dictyostelium cells
por: Chen, Suwei, et al.
Publicado: (2017)

A Literature Review of GP Knowledge and Understanding of ME/CFS: A Report from the Socioeconomic Working Group of the European Network on ME/CFS (EUROMENE)
por: Pheby, Derek F. H., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_c253nhc24god98j9k3v9glrb1f