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Lack of PKCθ Promotes Regenerative Ability of Muscle Stem Cells in Chronic Muscle Injury

Duchenne muscular dystrophy (DMD) is a genetic disease characterized by muscle wasting and chronic inflammation, leading to impaired satellite cells (SCs) function and exhaustion of their regenerative capacity. We previously showed that lack of PKCθ in mdx mice, a mouse model of DMD, reduces muscle...

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Detalles Bibliográficos
Autores principales: Fiore, Piera Filomena, Benedetti, Anna, Sandonà, Martina, Madaro, Luca, De Bardi, Marco, Saccone, Valentina, Puri, Pier Lorenzo, Gargioli, Cesare, Lozanoska-Ochser, Biliana, Bouché, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037041/
https://www.ncbi.nlm.nih.gov/pubmed/32023816
http://dx.doi.org/10.3390/ijms21030932