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Primary Cutaneous Anaplastic Large Cell Lymphoma (pcALCL) in the Elderly and the Importance of Sport Activity Training
Primary cutaneous anaplastic large cell lymphoma (pcALCL) is part of a spectrum of cutaneous CD30+ lymphoproliferative disease that also includes lymphomatoid papulosis. It often occurs in elderly patients, presenting at a median age of 60 years, although it may occur at any age. It is a CD30+ T-cel...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037068/ https://www.ncbi.nlm.nih.gov/pubmed/32013101 http://dx.doi.org/10.3390/ijerph17030839 |
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author | Sica, Antonello Vitiello, Paola Ronchi, Andrea Casale, Beniamino Calogero, Armando Sagnelli, Evangelista Costa Nachtigal, Gilca Troiani, Teresa Franco, Renato Argenziano, Giuseppe Moscarella, Elvira Sagnelli, Caterina |
author_facet | Sica, Antonello Vitiello, Paola Ronchi, Andrea Casale, Beniamino Calogero, Armando Sagnelli, Evangelista Costa Nachtigal, Gilca Troiani, Teresa Franco, Renato Argenziano, Giuseppe Moscarella, Elvira Sagnelli, Caterina |
author_sort | Sica, Antonello |
collection | PubMed |
description | Primary cutaneous anaplastic large cell lymphoma (pcALCL) is part of a spectrum of cutaneous CD30+ lymphoproliferative disease that also includes lymphomatoid papulosis. It often occurs in elderly patients, presenting at a median age of 60 years, although it may occur at any age. It is a CD30+ T-cell neoplasm composed of large cells with anaplastic, pleomorphic, or immunoblastic morphology, with exclusively cutaneous onset and localization. The clinical course of pcALCL is predominantly indolent. Most elderly patients with lymphoma tend to have a sedentary lifestyle, which has a negative effect on their quality of life (QoL) and survival. Several studies indicate that exercise has a positive impact on QoL because it reduces peak oxygen consumption, improves physical capacity, increases self-esteem, reduces accumulated stress, and promotes relaxation. Therefore, particularly in indolent lymphomas, it is necessary to indicate a program of physical activity to be practiced systematically. Complete surgical excision and local radiotherapy are the first line gold standard in pcALCL with a solitary lesion. |
format | Online Article Text |
id | pubmed-7037068 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-70370682020-03-11 Primary Cutaneous Anaplastic Large Cell Lymphoma (pcALCL) in the Elderly and the Importance of Sport Activity Training Sica, Antonello Vitiello, Paola Ronchi, Andrea Casale, Beniamino Calogero, Armando Sagnelli, Evangelista Costa Nachtigal, Gilca Troiani, Teresa Franco, Renato Argenziano, Giuseppe Moscarella, Elvira Sagnelli, Caterina Int J Environ Res Public Health Review Primary cutaneous anaplastic large cell lymphoma (pcALCL) is part of a spectrum of cutaneous CD30+ lymphoproliferative disease that also includes lymphomatoid papulosis. It often occurs in elderly patients, presenting at a median age of 60 years, although it may occur at any age. It is a CD30+ T-cell neoplasm composed of large cells with anaplastic, pleomorphic, or immunoblastic morphology, with exclusively cutaneous onset and localization. The clinical course of pcALCL is predominantly indolent. Most elderly patients with lymphoma tend to have a sedentary lifestyle, which has a negative effect on their quality of life (QoL) and survival. Several studies indicate that exercise has a positive impact on QoL because it reduces peak oxygen consumption, improves physical capacity, increases self-esteem, reduces accumulated stress, and promotes relaxation. Therefore, particularly in indolent lymphomas, it is necessary to indicate a program of physical activity to be practiced systematically. Complete surgical excision and local radiotherapy are the first line gold standard in pcALCL with a solitary lesion. MDPI 2020-01-29 2020-02 /pmc/articles/PMC7037068/ /pubmed/32013101 http://dx.doi.org/10.3390/ijerph17030839 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Sica, Antonello Vitiello, Paola Ronchi, Andrea Casale, Beniamino Calogero, Armando Sagnelli, Evangelista Costa Nachtigal, Gilca Troiani, Teresa Franco, Renato Argenziano, Giuseppe Moscarella, Elvira Sagnelli, Caterina Primary Cutaneous Anaplastic Large Cell Lymphoma (pcALCL) in the Elderly and the Importance of Sport Activity Training |
title | Primary Cutaneous Anaplastic Large Cell Lymphoma (pcALCL) in the Elderly and the Importance of Sport Activity Training |
title_full | Primary Cutaneous Anaplastic Large Cell Lymphoma (pcALCL) in the Elderly and the Importance of Sport Activity Training |
title_fullStr | Primary Cutaneous Anaplastic Large Cell Lymphoma (pcALCL) in the Elderly and the Importance of Sport Activity Training |
title_full_unstemmed | Primary Cutaneous Anaplastic Large Cell Lymphoma (pcALCL) in the Elderly and the Importance of Sport Activity Training |
title_short | Primary Cutaneous Anaplastic Large Cell Lymphoma (pcALCL) in the Elderly and the Importance of Sport Activity Training |
title_sort | primary cutaneous anaplastic large cell lymphoma (pcalcl) in the elderly and the importance of sport activity training |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037068/ https://www.ncbi.nlm.nih.gov/pubmed/32013101 http://dx.doi.org/10.3390/ijerph17030839 |
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