Cargando…

Primary Cutaneous Anaplastic Large Cell Lymphoma (pcALCL) in the Elderly and the Importance of Sport Activity Training

Primary cutaneous anaplastic large cell lymphoma (pcALCL) is part of a spectrum of cutaneous CD30+ lymphoproliferative disease that also includes lymphomatoid papulosis. It often occurs in elderly patients, presenting at a median age of 60 years, although it may occur at any age. It is a CD30+ T-cel...

Descripción completa

Detalles Bibliográficos
Autores principales: Sica, Antonello, Vitiello, Paola, Ronchi, Andrea, Casale, Beniamino, Calogero, Armando, Sagnelli, Evangelista, Costa Nachtigal, Gilca, Troiani, Teresa, Franco, Renato, Argenziano, Giuseppe, Moscarella, Elvira, Sagnelli, Caterina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037068/
https://www.ncbi.nlm.nih.gov/pubmed/32013101
http://dx.doi.org/10.3390/ijerph17030839
_version_ 1783500340906164224
author Sica, Antonello
Vitiello, Paola
Ronchi, Andrea
Casale, Beniamino
Calogero, Armando
Sagnelli, Evangelista
Costa Nachtigal, Gilca
Troiani, Teresa
Franco, Renato
Argenziano, Giuseppe
Moscarella, Elvira
Sagnelli, Caterina
author_facet Sica, Antonello
Vitiello, Paola
Ronchi, Andrea
Casale, Beniamino
Calogero, Armando
Sagnelli, Evangelista
Costa Nachtigal, Gilca
Troiani, Teresa
Franco, Renato
Argenziano, Giuseppe
Moscarella, Elvira
Sagnelli, Caterina
author_sort Sica, Antonello
collection PubMed
description Primary cutaneous anaplastic large cell lymphoma (pcALCL) is part of a spectrum of cutaneous CD30+ lymphoproliferative disease that also includes lymphomatoid papulosis. It often occurs in elderly patients, presenting at a median age of 60 years, although it may occur at any age. It is a CD30+ T-cell neoplasm composed of large cells with anaplastic, pleomorphic, or immunoblastic morphology, with exclusively cutaneous onset and localization. The clinical course of pcALCL is predominantly indolent. Most elderly patients with lymphoma tend to have a sedentary lifestyle, which has a negative effect on their quality of life (QoL) and survival. Several studies indicate that exercise has a positive impact on QoL because it reduces peak oxygen consumption, improves physical capacity, increases self-esteem, reduces accumulated stress, and promotes relaxation. Therefore, particularly in indolent lymphomas, it is necessary to indicate a program of physical activity to be practiced systematically. Complete surgical excision and local radiotherapy are the first line gold standard in pcALCL with a solitary lesion.
format Online
Article
Text
id pubmed-7037068
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-70370682020-03-11 Primary Cutaneous Anaplastic Large Cell Lymphoma (pcALCL) in the Elderly and the Importance of Sport Activity Training Sica, Antonello Vitiello, Paola Ronchi, Andrea Casale, Beniamino Calogero, Armando Sagnelli, Evangelista Costa Nachtigal, Gilca Troiani, Teresa Franco, Renato Argenziano, Giuseppe Moscarella, Elvira Sagnelli, Caterina Int J Environ Res Public Health Review Primary cutaneous anaplastic large cell lymphoma (pcALCL) is part of a spectrum of cutaneous CD30+ lymphoproliferative disease that also includes lymphomatoid papulosis. It often occurs in elderly patients, presenting at a median age of 60 years, although it may occur at any age. It is a CD30+ T-cell neoplasm composed of large cells with anaplastic, pleomorphic, or immunoblastic morphology, with exclusively cutaneous onset and localization. The clinical course of pcALCL is predominantly indolent. Most elderly patients with lymphoma tend to have a sedentary lifestyle, which has a negative effect on their quality of life (QoL) and survival. Several studies indicate that exercise has a positive impact on QoL because it reduces peak oxygen consumption, improves physical capacity, increases self-esteem, reduces accumulated stress, and promotes relaxation. Therefore, particularly in indolent lymphomas, it is necessary to indicate a program of physical activity to be practiced systematically. Complete surgical excision and local radiotherapy are the first line gold standard in pcALCL with a solitary lesion. MDPI 2020-01-29 2020-02 /pmc/articles/PMC7037068/ /pubmed/32013101 http://dx.doi.org/10.3390/ijerph17030839 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Sica, Antonello
Vitiello, Paola
Ronchi, Andrea
Casale, Beniamino
Calogero, Armando
Sagnelli, Evangelista
Costa Nachtigal, Gilca
Troiani, Teresa
Franco, Renato
Argenziano, Giuseppe
Moscarella, Elvira
Sagnelli, Caterina
Primary Cutaneous Anaplastic Large Cell Lymphoma (pcALCL) in the Elderly and the Importance of Sport Activity Training
title Primary Cutaneous Anaplastic Large Cell Lymphoma (pcALCL) in the Elderly and the Importance of Sport Activity Training
title_full Primary Cutaneous Anaplastic Large Cell Lymphoma (pcALCL) in the Elderly and the Importance of Sport Activity Training
title_fullStr Primary Cutaneous Anaplastic Large Cell Lymphoma (pcALCL) in the Elderly and the Importance of Sport Activity Training
title_full_unstemmed Primary Cutaneous Anaplastic Large Cell Lymphoma (pcALCL) in the Elderly and the Importance of Sport Activity Training
title_short Primary Cutaneous Anaplastic Large Cell Lymphoma (pcALCL) in the Elderly and the Importance of Sport Activity Training
title_sort primary cutaneous anaplastic large cell lymphoma (pcalcl) in the elderly and the importance of sport activity training
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037068/
https://www.ncbi.nlm.nih.gov/pubmed/32013101
http://dx.doi.org/10.3390/ijerph17030839
work_keys_str_mv AT sicaantonello primarycutaneousanaplasticlargecelllymphomapcalclintheelderlyandtheimportanceofsportactivitytraining
AT vitiellopaola primarycutaneousanaplasticlargecelllymphomapcalclintheelderlyandtheimportanceofsportactivitytraining
AT ronchiandrea primarycutaneousanaplasticlargecelllymphomapcalclintheelderlyandtheimportanceofsportactivitytraining
AT casalebeniamino primarycutaneousanaplasticlargecelllymphomapcalclintheelderlyandtheimportanceofsportactivitytraining
AT calogeroarmando primarycutaneousanaplasticlargecelllymphomapcalclintheelderlyandtheimportanceofsportactivitytraining
AT sagnellievangelista primarycutaneousanaplasticlargecelllymphomapcalclintheelderlyandtheimportanceofsportactivitytraining
AT costanachtigalgilca primarycutaneousanaplasticlargecelllymphomapcalclintheelderlyandtheimportanceofsportactivitytraining
AT troianiteresa primarycutaneousanaplasticlargecelllymphomapcalclintheelderlyandtheimportanceofsportactivitytraining
AT francorenato primarycutaneousanaplasticlargecelllymphomapcalclintheelderlyandtheimportanceofsportactivitytraining
AT argenzianogiuseppe primarycutaneousanaplasticlargecelllymphomapcalclintheelderlyandtheimportanceofsportactivitytraining
AT moscarellaelvira primarycutaneousanaplasticlargecelllymphomapcalclintheelderlyandtheimportanceofsportactivitytraining
AT sagnellicaterina primarycutaneousanaplasticlargecelllymphomapcalclintheelderlyandtheimportanceofsportactivitytraining