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Hepatotoxicity Modeling Using Counter-Propagation Artificial Neural Networks: Handling an Imbalanced Classification Problem

Drug-induced liver injury is a major concern in the drug development process. Expensive and time-consuming in vitro and in vivo studies do not reflect the complexity of the phenomenon. Complementary to wet lab methods are in silico approaches, which present a cost-efficient method for toxicity predi...

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Detalles Bibliográficos
Autores principales: Bajželj, Benjamin, Drgan, Viktor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037161/
https://www.ncbi.nlm.nih.gov/pubmed/31979300
http://dx.doi.org/10.3390/molecules25030481

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