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Molecular Interactions of Carbapenem Antibiotics with the Multidrug Efflux Transporter AcrB of Escherichia coli
The drug/proton antiporter AcrB, engine of the major efflux pump AcrAB(Z)-TolC of Escherichia coli and other bacteria, is characterized by its impressive ability to transport chemically diverse compounds, conferring a multi-drug resistance (MDR) phenotype. Although hundreds of small molecules are kn...
Autores principales: | Atzori, Alessio, Malloci, Giuliano, Cardamone, Francesca, Bosin, Andrea, Vargiu, Attilio Vittorio, Ruggerone, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037162/ https://www.ncbi.nlm.nih.gov/pubmed/32013182 http://dx.doi.org/10.3390/ijms21030860 |
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