Cargando…

Knockdown of FOXO6 Inhibits Glycolysis and Reduces Cell Resistance to Paclitaxel in HCC Cells via PI3K/Akt Signaling Pathway

PURPOSE: Previous studies have reported that FOXO6 is highly expressed in hepatocellular carcinoma (HCC) tissues and is associated with the prognosis of HCC patients. However, little research has been carried out to explore the role of FOXO6 in glycolysis of HCC cells and paclitaxel resistance. Toda...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Xixiang, Gao, Xixi, Mao, Xiaoping, Shi, Zhenjing, Zhu, Bangxuan, Xie, Linqin, Di, Shaodan, Jin, Limin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037170/ https://www.ncbi.nlm.nih.gov/pubmed/32110051 http://dx.doi.org/10.2147/OTT.S233031

Ejemplares similares

Juglanthraquinone C Induces Intracellular ROS Increase and Apoptosis by Activating the Akt/Foxo Signal Pathway in HCC Cells
por: Hou, Ya-Qin, et al.
Publicado: (2016)

Quercetin Inhibits the Proliferation of Glycolysis-Addicted HCC Cells by Reducing Hexokinase 2 and Akt-mTOR Pathway
por: Wu, Hongyan, et al.
Publicado: (2019)

GHR knockdown enhances the sensitivity of HCC cells to sorafenib
por: Gao, Shuang, et al.
Publicado: (2020)

CXCR4 knockdown enhances sensitivity of paclitaxel via the PI3K/Akt/mTOR pathway in ovarian carcinoma
por: Zi, Dan, et al.
Publicado: (2022)

The fatty acid receptor CD36 promotes HCC progression through activating Src/PI3K/AKT axis-dependent aerobic glycolysis
por: Luo, Xiaoqing, et al.
Publicado: (2021)

The Mechanism of Rac1 in Regulating HCC Cell Glycolysis Which Provides Underlying Therapeutic Target for HCC Therapy
por: Ren, Yin-Xiang, et al.
Publicado: (2022)

Correction for: CXCR4 knockdown enhances sensitivity of paclitaxel via the PI3K/Akt/mTOR pathway in ovarian carcinoma
por: Zi, Dan, et al.
Publicado: (2022)

Correction for: CXCR4 knockdown enhances sensitivity of paclitaxel via the PI3K/Akt/mTOR pathway in ovarian carcinoma
por: Zi, Dan, et al.
Publicado: (2023)

Knockdown of SETD5 inhibited glycolysis and tumor growth in gastric cancer cells by down-regulating Akt signaling pathway
por: Shi, Jing, et al.
Publicado: (2023)

TRIM15 forms a regulatory loop with the AKT/FOXO1 axis and LASP1 to modulate the sensitivity of HCC cells to TKIs
por: Yang, Chong, et al.
Publicado: (2023)

Overexpressed ITGA2 contributes to paclitaxel resistance by ovarian cancer cells through the activation of the AKT/FoxO1 pathway
por: Ma, Linlin, et al.
Publicado: (2020)

Exosomes from PYCR1 knockdown bone marrow mesenchymal stem inhibits aerobic glycolysis and the growth of bladder cancer cells via regulation of the EGFR/PI3K/AKT pathway
por: Li, Zhuo, et al.
Publicado: (2023)

PI3K/Akt signaling transduction pathway, erythropoiesis and glycolysis in hypoxia
por: Xie, Youbang, et al.
Publicado: (2019)

Correction for: Overexpressed ITGA2 contributes to paclitaxel resistance by ovarian cancer cells through the activation of the AKT/FoxO1 pathway
por: Ma, Linlin, et al.
Publicado: (2021)

Effects of metformin on the PI3K/AKT/FOXO1 pathway in anaplastic thyroid Cancer cell lines
por: Nozhat, Zahra, et al.
Publicado: (2018)

Knockdown of KLF5 suppresses hypoxia-induced resistance to cisplatin in NSCLC cells by regulating HIF-1α-dependent glycolysis through inactivation of the PI3K/Akt/mTOR pathway
por: Gong, Tianxiao, et al.
Publicado: (2018)

Enhancement of glycolysis-dependent DNA repair regulated by FOXO1 knockdown via PFKFB3 attenuates hyperglycemia-induced endothelial oxidative stress injury
por: Sun, Dandan, et al.
Publicado: (2022)

Knockdown of SLCO4C1 inhibits cell proliferation and metastasis in endometrial cancer through inactivating the PI3K/Akt signaling pathway
por: Hu, Xiang, et al.
Publicado: (2020)

Knockdown of STIL suppresses the progression of gastric cancer by down‐regulating the IGF‐1/PI3K/AKT pathway
por: Wang, Ju, et al.
Publicado: (2019)

Paclitaxel increases the sensitivity of lung cancer cells to lobaplatin via PI3K/Akt pathway
por: Ma, Dongjie, et al.
Publicado: (2018)

Paclitaxel increases the sensitivity of lung cancer cells to lobaplatin via PI3K/Akt pathway
por: Ma, Dongjie, et al.
Publicado: (2021)

Knockdown of NIR Suppresses Breast Cancer Cell Proliferation via Promoting FOXO3
por: Chen, Bolin, et al.
Publicado: (2021)

Hypoxia‐induced FOXO4/LDHA axis modulates gastric cancer cell glycolysis and progression
por: Wang, Xiao‐Hong, et al.
Publicado: (2021)

Cell type-specific regulation of CCN2 protein expression by PI3K–AKT–FoxO signaling
por: Samarin, Jana, et al.
Publicado: (2009)

HnRNP-F promotes the proliferation of bladder cancer cells mediated by PI3K/AKT/FOXO1
por: Li, Fei, et al.
Publicado: (2021)

Effects of circFOXO3 on the Proliferation and Invasion of Liver Cancer Cells by Regulating PI3K/Akt Pathway
por: Liu, Siyu, et al.
Publicado: (2022)

Kanglaite reverses multidrug resistance of HCC by inducing apoptosis and cell cycle arrest via PI3K/AKT pathway
por: Yang, Chendong, et al.
Publicado: (2018)

Knockdown of Ski decreases osteosarcoma cell proliferation and migration by suppressing the PI3K/Akt signaling pathway
por: Zhao, Xin, et al.
Publicado: (2019)

Embryonic liver fordin is involved in glucose glycolysis of hepatic stellate cell by regulating PI3K/Akt signaling
por: Tu, Wei, et al.
Publicado: (2016)

Retraction: Daphnetin inhibits proliferation and glycolysis in colorectal cancer cells by regulating the PI3K/Akt signaling pathway
por: Fisher, Laura
Publicado: (2021)

SETD1A promotes the proliferation and glycolysis of nasopharyngeal carcinoma cells by activating the PI3K/Akt pathway
por: Huang, Jianyi, et al.
Publicado: (2022)

PLEKHG2 Promotes NSCLC Cell Growth by Increasing Glycolysis via Activated PI3K/AKT Pathway
por: Xia, Yang, et al.
Publicado: (2023)

ARHGAP20 Expression Inhibited HCC Progression by Regulating the PI3K-AKT Signaling Pathway
por: Liu, Gao, et al.
Publicado: (2021)

Akt regulation of glycolysis mediates bioenergetic stability in epithelial cells
por: Hung, Yin P, et al.
Publicado: (2017)

Circular RNA FOXO3 accelerates glycolysis and improves cisplatin sensitivity in lung cancer cells via the miR-543/Foxo3 axis
por: Zhang, Yanni, et al.
Publicado: (2021)

MST4 negatively regulates the EMT, invasion and metastasis of HCC cells by inactivating PI3K/AKT/Snail1 axis
por: Dian, Mei-Juan, et al.
Publicado: (2021)

ARID4B Knockdown Suppresses PI3K/AKT Signaling and Induces Apoptosis in Human Glioma Cells
por: Luo, Siou-Min, et al.
Publicado: (2021)

Knockdown of SPOCK1 Inhibits the Proliferation and Invasion in Colorectal Cancer Cells by Suppressing the PI3K/Akt Pathway
por: Zhao, Ping, et al.
Publicado: (2016)

Retracted Article: Daphnetin inhibits proliferation and glycolysis in colorectal cancer cells by regulating the PI3K/Akt signaling pathway
por: He, Zhikuan, et al.
Publicado: (2018)

CircFOXO3 protects against osteoarthritis by targeting its parental gene FOXO3 and activating PI3K/AKT-mediated autophagy
por: Zhao, Chen, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_69jf2aohno5l5aolrltt8ohqk9