Cargando…

The Endocannabinoid System: A Target for Cancer Treatment

In recent years, the endocannabinoid system has received great interest as a potential therapeutic target in numerous pathological conditions. Cannabinoids have shown an anticancer potential by modulating several pathways involved in cell growth, differentiation, migration, and angiogenesis. However...

Descripción completa

Detalles Bibliográficos
Autores principales:	Laezza, Chiara, Pagano, Cristina, Navarra, Giovanna, Pastorino, Olga, Proto, Maria Chiara, Fiore, Donatella, Piscopo, Chiara, Gazzerro, Patrizia, Bifulco, Maurizio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037210/ https://www.ncbi.nlm.nih.gov/pubmed/31979368 http://dx.doi.org/10.3390/ijms21030747

Ejemplares similares

Lipid homeostasis and mevalonate pathway in COVID-19: Basic concepts and potential therapeutic targets
por: Proto, Maria Chiara, et al.
Publicado: (2021)

Modified Adenosines Sensitize Glioblastoma Cells to Temozolomide by Affecting DNA Methyltransferases
por: Proto, Maria Chiara, et al.
Publicado: (2022)

N6-Isopentenyladenosine Inhibits Colorectal Cancer and Improves Sensitivity to 5-Fluorouracil Targeting FBXW7 Tumor Suppressor
por: Fiore, Donatella, et al.
Publicado: (2019)

Commentary: Use of Cannabinoids to Treat Acute Respiratory Distress Syndrome and Cytokine Storm Associated With Coronavirus Disease-2019
por: Bifulco, Maurizio, et al.
Publicado: (2021)

N(6)-Isopentenyladenosine Enhances the Radiosensitivity of Glioblastoma Cells by Inhibiting the Homologous Recombination Repair Protein RAD51 Expression
por: Navarra, Giovanna, et al.
Publicado: (2020)

Inhibition of Wnt/β-Catenin pathway and Histone acetyltransferase activity by Rimonabant: a therapeutic target for colon cancer
por: Proto, Maria Chiara, et al.
Publicado: (2017)

Rimonabant and Cannabidiol Rewrite the Interactions between Breast Cancer Cells and Tumor Microenvironment
por: Proto, Maria Chiara, et al.
Publicado: (2023)

Association of Alpha B-Crystallin Expression with Tumor Differentiation Grade in Colorectal Cancer Patients
por: Pagano, Cristina, et al.
Publicado: (2021)

In Vitro Evidence of Statins’ Protective Role against COVID-19 Hallmarks Comptes Rendus
por: Fiore, Donatella, et al.
Publicado: (2022)

Molecular Mechanism of Cannabinoids in Cancer Progression
por: Pagano, Cristina, et al.
Publicado: (2021)

N6-Isopentenyladenosine Hinders the Vasculogenic Mimicry in Human Glioblastoma Cells through Src-120 Catenin Pathway Modulation and RhoA Activity Inhibition
por: Pagano, Cristina, et al.
Publicado: (2021)

Rimonabant Kills Colon Cancer Stem Cells without Inducing Toxicity in Normal Colon Organoids
por: Fiore, Donatella, et al.
Publicado: (2018)

Cannabinoid receptor CB1 regulates STAT3 activity and its expression dictates the responsiveness to SR141716 treatment in human glioma patients' cells
por: Ciaglia, Elena, et al.
Publicado: (2015)

Cannabinoids: Therapeutic Use in Clinical Practice
por: Pagano, Cristina, et al.
Publicado: (2022)

Cannabinoids in the Modulation of Oxidative Signaling
por: Pagano, Cristina, et al.
Publicado: (2023)

N6-isopentenyladenosine induces cell death through necroptosis in human glioblastoma cells
por: Pagano, Cristina, et al.
Publicado: (2022)

Multifaceted Role of PRDM Proteins in Human Cancer
por: Casamassimi, Amelia, et al.
Publicado: (2020)

Impacts of Environmental Pollution on Brain Tumorigenesis
por: Pagano, Cristina, et al.
Publicado: (2023)

Immuno-Modulatory and Anti-Inflammatory Effects of Dihydrogracilin A, a Terpene Derived from the Marine Sponge Dendrilla membranosa
por: Ciaglia, Elena, et al.
Publicado: (2017)

Effects on Immune Cells of a New 1,8-Naphthyridin-2-One Derivative and Its Analogues as Selective CB2 Agonists: Implications in Multiple Sclerosis
por: Malfitano, Anna Maria, et al.
Publicado: (2013)

Deregulated expression and activity of Farnesyl Diphosphate Synthase (FDPS) in Glioblastoma
por: Abate, Mario, et al.
Publicado: (2017)

Cholesterol Homeostasis Modulates Platinum Sensitivity in Human Ovarian Cancer
por: Criscuolo, Daniela, et al.
Publicado: (2020)

Statins in coronavirus outbreak: It’s time for experimental and clinical studies
por: Bifulco, Maurizio, et al.
Publicado: (2020)

RIZ2 at the crossroad of the EGF/EGFR signaling in colorectal cancer
por: Di Donato, Marzia, et al.
Publicado: (2023)

Cannabinoids in the management of spasticity associated with multiple sclerosis
por: Malfitano, Anna Maria, et al.
Publicado: (2008)

Towards an Improvement of Anticancer Activity of Benzyl Adenosine Analogs
por: Covelli, Verdiana, et al.
Publicado: (2021)

N6-Isopentenyladenosine Impairs Mitochondrial Metabolism through Inhibition of EGFR Translocation on Mitochondria in Glioblastoma Cells
por: Pagano, Cristina, et al.
Publicado: (2022)

Endocannabinoid System and Migraine Pain: An Update
por: Greco, Rosaria, et al.
Publicado: (2018)

The Endocannabinoid System in Pediatric Inflammatory and Immune Diseases
por: Argenziano, Maura, et al.
Publicado: (2019)

The Endocannabinoid/Endovanilloid System in Bone: From Osteoporosis to Osteosarcoma
por: Rossi, Francesca, et al.
Publicado: (2019)

Endocannabinoid System as Therapeutic Target of PTSD: A Systematic Review
por: Steardo, Luca, et al.
Publicado: (2021)

Genetic and pharmacological regulation of the endocannabinoid CB1 receptor in Duchenne muscular dystrophy
por: Iannotti, Fabio A., et al.
Publicado: (2018)

The benefit of statins in SARS-CoV-2 patients: further metabolic and prospective clinical studies are needed
por: Bifulco, Maurizio, et al.
Publicado: (2020)

PRDM12 in Health and Diseases
por: Rienzo, Monica, et al.
Publicado: (2021)

The Endocannabinoid System: A Potential Target for the Treatment of Various Diseases
por: Lowe, Henry, et al.
Publicado: (2021)

PR/SET Domain Family and Cancer: Novel Insights from The Cancer Genome Atlas
por: Sorrentino, Anna, et al.
Publicado: (2018)

Editorial of the Special Issue “Targeted Therapies for Cancer”
por: Pastorino, Fabio, et al.
Publicado: (2022)

Nanocarrier-Mediated Targeting of Tumor and Tumor Vascular Cells Improves Uptake and Penetration of Drugs into Neuroblastoma
por: Pastorino, Fabio, et al.
Publicado: (2013)

Prenatal Stress and Peripubertal Stimulation of the Endocannabinoid System Differentially Regulate Emotional Responses and Brain Metabolism in Mice
por: Macrì, Simone, et al.
Publicado: (2012)

The Endocannabinoid System as a Therapeutic Target in Glaucoma
por: Cairns, Elizabeth A., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_4r8tdgt0u6113iiogj2rvk547b