Collective cancer invasion forms an integrin-dependent radioresistant niche

Cancer fatalities result from metastatic dissemination and therapy resistance, both processes that depend on signals from the tumor microenvironment. To identify how invasion and resistance programs cooperate, we used intravital microscopy of orthotopic sarcoma and melanoma xenografts. We demonstrat...

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Detalles Bibliográficos
Autores principales: Haeger, Anna, Alexander, Stephanie, Vullings, Manon, Kaiser, Fabian M.P., Veelken, Cornelia, Flucke, Uta, Koehl, Gudrun E., Hirschberg, Markus, Flentje, Michael, Hoffman, Robert M., Geissler, Edward K., Kissler, Stephan, Friedl, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037234/
https://www.ncbi.nlm.nih.gov/pubmed/31658985
http://dx.doi.org/10.1084/jem.20181184

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