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Interleukin-15 (dys)regulation of lymphoid homeostasis: Implications for therapy of autoimmunity and cancer

IL-15, a pleiotropic cytokine, stimulates generation of NK, NK-T, γδ, ILC1, and memory CD8 T cells. IL-15 disorders play pathogenetic roles in organ-specific autoimmune diseases including celiac disease. Diverse approaches are developed to block IL-15 action. IL-15 administered to patients with mali...

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Detalles Bibliográficos
Autores principales:	Waldmann, Thomas A., Miljkovic, Milos D., Conlon, Kevin C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2019
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037239/ https://www.ncbi.nlm.nih.gov/pubmed/31821442 http://dx.doi.org/10.1084/jem.20191062

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