Cargando…

Switch hitter: Bcl11b in T cells and ILC2s

In this issue of JEM, Hosokawa et al. (https://doi.org/10.1084/jem.20190972) establish that transcription factor Bcl11b regulates almost completely distinct sets of genes in T cell precursors and ILC2s. To understand how this occurs, they identify multiple levels of functional regulation for Bcl11b...

Descripción completa

Detalles Bibliográficos
Autores principales: Harly, Christelle, Bhandoola, Avinash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037246/
https://www.ncbi.nlm.nih.gov/pubmed/31828302
http://dx.doi.org/10.1084/jem.20191739
_version_ 1783500382352179200
author Harly, Christelle
Bhandoola, Avinash
author_facet Harly, Christelle
Bhandoola, Avinash
author_sort Harly, Christelle
collection PubMed
description In this issue of JEM, Hosokawa et al. (https://doi.org/10.1084/jem.20190972) establish that transcription factor Bcl11b regulates almost completely distinct sets of genes in T cell precursors and ILC2s. To understand how this occurs, they identify multiple levels of functional regulation for Bcl11b that are used differently by T cell precursors and ILC2s.
format Online
Article
Text
id pubmed-7037246
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-70372462020-07-06 Switch hitter: Bcl11b in T cells and ILC2s Harly, Christelle Bhandoola, Avinash J Exp Med News In this issue of JEM, Hosokawa et al. (https://doi.org/10.1084/jem.20190972) establish that transcription factor Bcl11b regulates almost completely distinct sets of genes in T cell precursors and ILC2s. To understand how this occurs, they identify multiple levels of functional regulation for Bcl11b that are used differently by T cell precursors and ILC2s. Rockefeller University Press 2019-12-11 /pmc/articles/PMC7037246/ /pubmed/31828302 http://dx.doi.org/10.1084/jem.20191739 Text en © 2019 Harly and Bhandoola http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle News
Harly, Christelle
Bhandoola, Avinash
Switch hitter: Bcl11b in T cells and ILC2s
title Switch hitter: Bcl11b in T cells and ILC2s
title_full Switch hitter: Bcl11b in T cells and ILC2s
title_fullStr Switch hitter: Bcl11b in T cells and ILC2s
title_full_unstemmed Switch hitter: Bcl11b in T cells and ILC2s
title_short Switch hitter: Bcl11b in T cells and ILC2s
title_sort switch hitter: bcl11b in t cells and ilc2s
topic News
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037246/
https://www.ncbi.nlm.nih.gov/pubmed/31828302
http://dx.doi.org/10.1084/jem.20191739
work_keys_str_mv AT harlychristelle switchhitterbcl11bintcellsandilc2s
AT bhandoolaavinash switchhitterbcl11bintcellsandilc2s