Cell type–specific actions of Bcl11b in early T-lineage and group 2 innate lymphoid cells

The zinc finger transcription factor, Bcl11b, is expressed in T cells and group 2 innate lymphoid cells (ILC2s) among hematopoietic cells. In early T-lineage cells, Bcl11b directly binds and represses the gene encoding the E protein antagonist, Id2, preventing pro-T cells from adopting innate-like f...

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Detalles Bibliográficos
Autores principales: Hosokawa, Hiroyuki, Romero-Wolf, Maile, Yang, Qi, Motomura, Yasutaka, Levanon, Ditsa, Groner, Yoram, Moro, Kazuyo, Tanaka, Tomoaki, Rothenberg, Ellen V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037248/
https://www.ncbi.nlm.nih.gov/pubmed/31653691
http://dx.doi.org/10.1084/jem.20190972

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