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Developmental and cellular age direct conversion of CD4(+) T cells into RORγ(+) or Helios(+) colon Treg cells

RORγ(+) and Helios(+) Treg cells in the colon are phenotypically and functionally distinct, but their origins and relationships are poorly understood. In monocolonized and normal mice, single-cell RNA-seq revealed sharing of TCR clonotypes between these Treg cell populations, potentially denoting a...

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Detalles Bibliográficos
Autores principales:	Pratama, Alvin, Schnell, Alexandra, Mathis, Diane, Benoist, Christophe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037252/ https://www.ncbi.nlm.nih.gov/pubmed/31685531 http://dx.doi.org/10.1084/jem.20190428

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