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Rapid and Effective Generation of Nanobody Based CARs using PCR and Gibson Assembly

Recent approval of chimeric antigen receptor (CAR) T cell therapy by the European Medicines Agency (EMA)/Federal and Drug Administration (FDA) and the remarkable results of CAR T clinical trials illustrate the curative potential of this therapy. While CARs against a multitude of different antigens a...

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Detalles Bibliográficos
Autores principales: De Munter, Stijn, Van Parys, Alexander, Bral, Layla, Ingels, Joline, Goetgeluk, Glenn, Bonte, Sarah, Pille, Melissa, Billiet, Lore, Weening, Karin, Verhee, Annick, Van der Heyden, Jose, Taghon, Tom, Leclercq, Georges, Kerre, Tessa, Tavernier, Jan, Vandekerckhove, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037261/
https://www.ncbi.nlm.nih.gov/pubmed/32019116
http://dx.doi.org/10.3390/ijms21030883