Alpha-1 Antitrypsin—A Target for MicroRNA-Based Therapeutic Development for Cystic Fibrosis

Cystic fibrosis (CF) is an autosomal recessive genetic disorder arising from mutations to the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Disruption to normal ion homeostasis in the airway results in impaired mucociliary clearance, leaving the lung more vulnerable to recurrent a...

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Detalles Bibliográficos
Autores principales: Hunt, Alison M.D., Glasgow, Arlene M.A., Humphreys, Hilary, Greene, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037267/
https://www.ncbi.nlm.nih.gov/pubmed/32012925
http://dx.doi.org/10.3390/ijms21030836

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