Human-Induced Neurons from Presenilin 1 Mutant Patients Model Aspects of Alzheimer’s Disease Pathology

Traditional approaches to studying Alzheimer’s disease (AD) using mouse models and cell lines have advanced our understanding of AD pathogenesis. However, with the growing divide between model systems and clinical therapeutic outcomes, the limitations of these approaches are increasingly apparent. T...

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Detalles Bibliográficos
Autores principales: Schrank, Sean, McDaid, John, Briggs, Clark A., Mustaly-Kalimi, Sarah, Brinks, Deanna, Houcek, Aiden, Singer, Oded, Bottero, Virginie, Marr, Robert A., Stutzmann, Grace E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037274/
https://www.ncbi.nlm.nih.gov/pubmed/32033164
http://dx.doi.org/10.3390/ijms21031030

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