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Intracellular Calcium Dysregulation by the Alzheimer’s Disease-Linked Protein Presenilin 2
Alzheimer’s disease (AD) is the most common form of dementia. Even though most AD cases are sporadic, a small percentage is familial due to autosomal dominant mutations in amyloid precursor protein (APP), presenilin-1 (PSEN1), and presenilin-2 (PSEN2) genes. AD mutations contribute to the generation...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037278/ https://www.ncbi.nlm.nih.gov/pubmed/31991578 http://dx.doi.org/10.3390/ijms21030770 |