Development and Validation of Analytical Method for SH-1242 in the Rat and Mouse Plasma by Liquid Chromatography/Tandem Mass Spectrometry

SH-1242, a novel inhibitor of heat shock protein 90 (HSP90), is a synthetic analog of deguelin: It was previously reported that the treatment of SH-1242 led to a strong suppression of hypoxia-mediated retinal neovascularization and vascular leakage in diabetic retinas by inhibiting the hypoxia-induc...

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Detalles Bibliográficos
Autores principales: Jeong, Yoo-Seong, Baek, Minjeong, Lee, Seungbeom, Kim, Min-Soo, Maeng, Han-Joo, Lee, Jong-Hwa, Suh, Young-Ger, Chung, Suk-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037321/
https://www.ncbi.nlm.nih.gov/pubmed/31991809
http://dx.doi.org/10.3390/molecules25030531

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