Cargando…

Rapid identification of chemical profile in Gandou decoction by UPLC-Q-TOF-MS(E) coupled with novel informatics UNIFI platform

Gandou decoction (GDD), a well-known traditional Chinese medicine (TCM) formula, has been widely used for decades to treat Wilson's disease (WD) in China due to its remarkable clinical effects. However, the chemical constituents of GDD still remain unclear because of their complexity. In this w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Li, Liu, Yi, Wu, Hongfei, Wu, Huan, Liu, Xiaochuang, Zhou, An
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Xi'an Jiaotong University 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037531/ https://www.ncbi.nlm.nih.gov/pubmed/32123598 http://dx.doi.org/10.1016/j.jpha.2019.05.003

Ejemplares similares

Identification and Analysis of Chemical Constituents and Rat Serum Metabolites in Gushuling Using UPLC-Q-TOF/MS Coupled with Novel Informatics UNIFI Platform
por: Chang, Hong, et al.
Publicado: (2021)

Identification of chemical components and rat serum metabolites in Danggui Buxue decoction based on UPLC-Q-TOF-MS, the UNIFI platform and molecular networks
por: Lv, Yanhui, et al.
Publicado: (2023)

Gandou Decoction Decreases Copper Levels and Alleviates Hepatic Injury in Copper-Laden Hepatolenticular Degeneration Model Rats
por: Wang, Na, et al.
Publicado: (2020)

Protective Mechanism of Gandou Decoction in a Copper-Laden Hepatolenticular Degeneration Model: In Vitro Pharmacology and Cell Metabolomics
por: Yin, Fengxia, et al.
Publicado: (2022)

Combination of UPLC–Q-TOF/MS and Network Pharmacology to Reveal the Mechanism of Qizhen Decoction in the Treatment of Colon Cancer
por: Kong, Xianbin, et al.
Publicado: (2021)

Profiling and Pharmacokinetic Studies of Alkaloids in Rats After Oral Administration of Zanthoxylum nitidum Decoction by UPLC-Q-TOF-MS/MS and HPLC-MS/MS
por: Huang, Aihua, et al.
Publicado: (2019)

Identification of Sanguinarine Metabolites in Rats Using UPLC-Q-TOF-MS/MS
por: Liu, Mengting, et al.
Publicado: (2023)

Serum Pharmacochemistry Analysis Using UPLC-Q-TOF/MS after Oral Administration to Rats of Shenfu Decoction
por: He, Jia-le, et al.
Publicado: (2015)

Identification of prototype compounds and their metabolites in rats’ serum from Xuefu Zhuyu Decoction by UPLC-Q-TOF/MS
por: Zhang, Xiaoyu, et al.
Publicado: (2022)

Metabolomics Study of Shaoyao Plants Decoction on the Proximal and Distal Colon in Mice with Dextran Sulfate Sodium-Induced Colitis by UPLC-Q-TOF-MS
por: Luo, Yiting, et al.
Publicado: (2022)

Determination of Progestin Residues in Fish by UPLC-Q-TOF/MS Coupled with QuEChERS
por: Gu, Chunxiu, et al.
Publicado: (2019)

Simultaneous Analysis of Iridoid Glycosides and Anthraquinones in Morinda officinalis Using UPLC-QqQ-MS/MS and UPLC-Q/TOF-MS(E)
por: Zhao, Xiangsheng, et al.
Publicado: (2018)

Metabolite Profiling and Distribution of Militarine in Rats Using UPLC-Q-TOF-MS/MS
por: Li, Limin, et al.
Publicado: (2020)

Quality Evaluation of Tricholoma matsutake Based on the Nucleic Acid Compounds by UPLC-TOF/MS and UPLC-QqQ/MS
por: Xue, Ying, et al.
Publicado: (2018)

UPLC-Q-TOF/MS Based Plasma Metabolomics for Identification of Paeonol’s Metabolic Target in Endometriosis
por: Liu, Jing, et al.
Publicado: (2023)

Chemical Profiling of Xueshuan Xinmaining Tablet by HPLC and UPLC-ESI-Q-TOF/MS
por: Han, Ya-Xin, et al.
Publicado: (2018)

UPLC-Q-TOF-MS Study of the Mechanism of THSWD for Breast Cancer Treatment
por: Duan, Xianchun, et al.
Publicado: (2020)

Identification of absorbed constituents and evaluation of the pharmacokinetics of main compounds after oral administration of yindanxinnaotong by UPLC-Q-TOF-MS and UPLC-QqQ-MS
por: Gong, Leilei, et al.
Publicado: (2018)

Integrating network pharmacology, UPLC-Q–TOF–MS and molecular docking to investigate the effect and mechanism of Chuanxiong Renshen decoction against Alzheimer's disease
por: Shen, Zhuo Jun, et al.
Publicado: (2022)

Metabolic profiling and pharmacokinetic studies of Baihu-Guizhi decoction in rats by UFLC-Q-TOF–MS/MS and UHPLC-Q-TRAP-MS/MS
por: He, Yan, et al.
Publicado: (2022)

Serum biomarkers of the calcium-deficient rats identified by metabolomics based on UPLC/Q-TOF MS/MS
por: Meng, Fanyu, et al.
Publicado: (2020)

Assessing the quality of Smilacis Glabrae Rhizoma (Tufuling) by colormetrics and UPLC-Q-TOF-MS
por: He, Xicheng, et al.
Publicado: (2016)

Evaluation of Microbial Transformation of 10-deoxoartemisinin by UPLC-ESI-Q-TOF-MS(E)
por: Bai, Yue, et al.
Publicado: (2019)

Comprehensive metabolomics study on the pathogenesis of anaplastic astrocytoma via UPLC-Q/TOF-MS
por: Du, Chao, et al.
Publicado: (2022)

Quality control of Semen Ziziphi Spinosae standard decoction based on determination of multi-components using TOF-MS/MS and UPLC-PDA technology
por: Wang, Di, et al.
Publicado: (2019)

Exploring potential mechanism of ciwujia tablets for insomnia by UPLC-Q-TOF-MS/MS, network pharmacology, and experimental validation
por: Liu, Hongda, et al.
Publicado: (2022)

Analysis of the Effect of (60)Co-γ Irradiation Sterilization Technology on the Chemical Composition of Saffron Using UPLC and UPLC/Q-TOF-MS
por: Luo, Ding-qiang, et al.
Publicado: (2018)

Qualitative and Quantitative Analysis of the Major Constituents in Shexiang Tongxin Dropping Pill by HPLC-Q-TOF-MS/MS and UPLC-QqQ-MS/MS
por: Chen, Daxin, et al.
Publicado: (2015)

Secondary Metabolite Profiling of Curcuma Species Grown at Different Locations Using GC/TOF and UPLC/Q-TOF MS
por: Lee, Jueun, et al.
Publicado: (2014)

Plasma metabolic profiling analysis of Cortex Periplocae-induced cardiotoxicity based on UPLC/Q-TOF-MS
por: Li, Yubo, et al.
Publicado: (2018)

Screening anti-fatigue components of American ginseng saponin by analyzing spectrum–effect relationship coupled with UPLC-Q-TOF-MS
por: Lin, Meiyu, et al.
Publicado: (2023)

Protective Effects of Protopanaxatriol Saponins on Ulcerative Colitis in Mouse Based on UPLC-Q/TOF-MS Serum and Colon Metabolomics
por: Wu, Fulin, et al.
Publicado: (2022)

Metabolomics Study of Different Germplasm Resources for Three Polygonatum Species Using UPLC-Q-TOF-MS/MS
por: Wang, Shiqiang, et al.
Publicado: (2022)

Qualitative and Quantitative Analysis of 24 Components in Jinlianhua Decoction by UPLC–MS/MS
por: Fang, Mingyue, et al.
Publicado: (2019)

Metabolomics Analysis of Morchella sp. From Different Geographical Origins of China Using UPLC-Q-TOF-MS
por: Dong, Hui, et al.
Publicado: (2022)

Antihepatotoxic Effect and Metabolite Profiling of Panicum turgidum Extract via UPLC-qTOF-MS
por: Farag, Mohamed A., et al.
Publicado: (2016)

Sphingolipidomic Profiling of Rat Serum by UPLC-Q-TOF-MS: Application to Rheumatoid Arthritis Study
por: Qu, Fanghui, et al.
Publicado: (2018)

UPLC/Q-TOF-MS based plasma metabolomics and clinical characteristics of polycystic ovarian syndrome
por: Fan, Xuemei, et al.
Publicado: (2019)

Simultaneous Determination of Ferulic Acid and Phthalides of Angelica Sinensis Based on UPLC-Q-TOF/MS
por: Wei, Wen-Long, et al.
Publicado: (2015)

UPLC-Q-TOF/MS-Based Metabolomics Approach to Reveal the Hepatotoxicity of Emodin and Detoxification of Dihydromyricetin
por: Gao, Jian, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_tibciproqu8t2oi2db2c6l876b