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miR-21-KO Alleviates Alveolar Structural Remodeling and Inflammatory Signaling in Acute Lung Injury

Acute lung injury (ALI) is characterized by enhanced permeability of the air–blood barrier, pulmonary edema, and hypoxemia. MicroRNA-21 (miR-21) was shown to be involved in pulmonary remodeling and the pathology of ALI, and we hypothesized that miR-21 knock-out (KO) reduces injury and remodeling in...

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Detalles Bibliográficos
Autores principales: Jansing, Johanna Christine, Fiedler, Jan, Pich, Andreas, Viereck, Janika, Thum, Thomas, Mühlfeld, Christian, Brandenberger, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037600/
https://www.ncbi.nlm.nih.gov/pubmed/32012801
http://dx.doi.org/10.3390/ijms21030822