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miR-21-KO Alleviates Alveolar Structural Remodeling and Inflammatory Signaling in Acute Lung Injury
Acute lung injury (ALI) is characterized by enhanced permeability of the air–blood barrier, pulmonary edema, and hypoxemia. MicroRNA-21 (miR-21) was shown to be involved in pulmonary remodeling and the pathology of ALI, and we hypothesized that miR-21 knock-out (KO) reduces injury and remodeling in...
Autores principales: | Jansing, Johanna Christine, Fiedler, Jan, Pich, Andreas, Viereck, Janika, Thum, Thomas, Mühlfeld, Christian, Brandenberger, Christina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037600/ https://www.ncbi.nlm.nih.gov/pubmed/32012801 http://dx.doi.org/10.3390/ijms21030822 |
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