Chemically Crosslinked Bispecific Antibodies for Cancer Therapy: Breaking from the Structural Restrictions of the Genetic Fusion Approach

Antibodies are composed of structurally and functionally independent domains that can be used as building blocks to construct different types of chimeric protein-format molecules. However, the generally used genetic fusion and chemical approaches restrict the types of structures that can be formed a...

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Detalles Bibliográficos
Autores principales: Ueda, Asami, Umetsu, Mitsuo, Nakanishi, Takeshi, Hashikami, Kentaro, Nakazawa, Hikaru, Hattori, Shuhei, Asano, Ryutaro, Kumagai, Izumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037651/
https://www.ncbi.nlm.nih.gov/pubmed/31973200
http://dx.doi.org/10.3390/ijms21030711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037651/
https://www.ncbi.nlm.nih.gov/pubmed/31973200
http://dx.doi.org/10.3390/ijms21030711

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