Cargando…
Targeting Macromolecules to CNS and Other Hard-to-Treat Organs Using Lectin-Mediated Delivery
The greatest challenges for therapeutic efficacy of many macromolecular drugs that act on intracellular are delivery to key organs and tissues and delivery into cells and subcellular compartments. Transport of drugs into critical cells associated with disease, including those in organs protected by...
Autores principales: | Acosta, Walter, Cramer, Carole L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037663/ https://www.ncbi.nlm.nih.gov/pubmed/32024082 http://dx.doi.org/10.3390/ijms21030971 |
Ejemplares similares
-
RTB Lectin: a novel receptor-independent delivery system for lysosomal enzyme replacement therapies
por: Acosta, Walter, et al.
Publicado: (2015) -
Preclinical Enzyme Replacement Therapy with a Recombinant β-Galactosidase-Lectin Fusion for CNS Delivery and Treatment of GM1-Gangliosidosis
por: Weesner, Jason Andrew, et al.
Publicado: (2022) -
The Configuration of the Perivascular System Transporting Macromolecules in the CNS
por: Durcanova, Beata, et al.
Publicado: (2019) -
Macromolecules as targeted drugs delivery vehicles: an overview
por: Ali, Yousaf, et al.
Publicado: (2019) -
Carriers for the targeted delivery of aerosolized macromolecules for pulmonary pathologies
por: Osman, Nashwa, et al.
Publicado: (2018)