Cargando…

The β-Blocker Carvedilol Prevented Ultraviolet-Mediated Damage of Murine Epidermal Cells and 3D Human Reconstructed Skin

The β-blocker carvedilol prevents ultraviolet (UV)-induced skin cancer, but the mechanism is unknown. Since carvedilol possesses antioxidant activity, this study investigated whether carvedilol prevents oxidative photodamage of skin, a precursor event in skin carcinogenesis. The effects of carvedilo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Mengbing, Liang, Sherry, Shahid, Ayaz, Andresen, Bradley T., Huang, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037760/ https://www.ncbi.nlm.nih.gov/pubmed/31991834 http://dx.doi.org/10.3390/ijms21030798

Ejemplares similares

The β-Blocker Carvedilol Prevents Benzo(a)pyrene-Induced Lung Toxicity, Inflammation and Carcinogenesis
por: Shahid, Ayaz, et al.
Publicado: (2023)

Topical Delivery of Carvedilol Loaded Nano-Transfersomes for Skin Cancer Chemoprevention
por: Chen, Mengbing, et al.
Publicado: (2020)

Transfersome Encapsulated with the R-carvedilol Enantiomer for Skin Cancer Chemoprevention
por: Shamim, Md Abdullah, et al.
Publicado: (2023)

Repositioning of the β-Blocker Carvedilol as a Novel Autophagy Inducer That Inhibits the NLRP3 Inflammasome
por: Wong, Wei-Ting, et al.
Publicado: (2018)

Ultraviolet Radiation-Induced Skin Aging: The Role of DNA Damage and Oxidative Stress in Epidermal Stem Cell Damage Mediated Skin Aging
por: Panich, Uraiwan, et al.
Publicado: (2016)

Carvedilol inhibits EGF-mediated JB6 P+ colony formation through a mechanism independent of adrenoceptors
por: Cleveland, Kristan H., et al.
Publicado: (2019)

The β-blocker carvedilol and the benznidazole modulate the cardiac immune response in the acute infection induced by Colombian strain of the Trypanosoma cruzi
por: Horta, Aline Luciano, et al.
Publicado: (2018)

Enantioselective Resolution of (R,S)-Carvedilol to (S)-(−)-Carvedilol by Biocatalysts
por: Ettireddy, Swetha, et al.
Publicado: (2017)

Edible bird’s nest extract downregulates epidermal apoptosis and helps reduce damage by ultraviolet radiation in skin of hairless mice
por: Masuda, Shinya, et al.
Publicado: (2022)

Unique Positive Cooperativity Between the β-Arrestin–Biased β-Blocker Carvedilol and a Small Molecule Positive Allosteric Modulator of the β2-Adrenergic Receptor
por: Pani, Biswaranjan, et al.
Publicado: (2021)

Effect of hydroxylpropyl-β-cyclodextrin on Solubility of Carvedilol
por: Shewale, B. D., et al.
Publicado: (2008)

How Carvedilol activates β(2)-adrenoceptors
por: Benkel, Tobias, et al.
Publicado: (2022)

Protective Effects of Vasodilatory Βeta-Blockers Carvedilol and Nebivolol against Glycerol Model of Rhabdomyolysis-Induced Acute Renal Failure in Rats
por: Atwa, Ahmed, et al.
Publicado: (2016)

The medicinal mushroom Ganoderma lucidum prevents lung tumorigenesis induced by tobacco smoke carcinogens
por: Shahid, Ayaz, et al.
Publicado: (2023)

The β-blocker Nebivolol Is a GRK/β-arrestin Biased Agonist
por: Erickson, Catherine E., et al.
Publicado: (2013)

Carvedilol Prevents Redox Inactivation of Cardiomyocyte Β(1)-Adrenergic Receptors
por: Park, Misun, et al.
Publicado: (2018)

Effect of adrenergic blockers, carvedilol, prazosin, metoprolol and combination of prazosin and metoprolol on paracetamol-induced hepatotoxicity in rabbits
por: Zubairi, Maysaa B., et al.
Publicado: (2014)

Protective role of beta-blockers in chemotherapy-induced cardiotoxicity—a systematic review and meta-analysis of carvedilol
por: Huang, Shan, et al.
Publicado: (2018)

Effects of the beta-blocker carvedilol on arrhythmia and long-term clinical outcomes in benign prostate hypertrophy patients
por: Kim, Soo Jin, et al.
Publicado: (2023)

Carvedilol, an Adrenergic Blocker, Suppresses Melanin Synthesis by Inhibiting the cAMP/CREB Signaling Pathway in Human Melanocytes and Ex Vivo Human Skin Culture
por: Choi, Myoung Eun, et al.
Publicado: (2020)

Enzymatically synthesized glycogen prevents ultraviolet B-induced cell damage in normal human epidermal keratinocytes
por: Yoshioka, Yasukiyo, et al.
Publicado: (2020)

How carvedilol does not activate β(2)-adrenoceptors
por: Lefkowitz, Robert J., et al.
Publicado: (2023)

Ultraviolet Radiation, Aging and the Skin: Prevention of Damage by Topical cAMP Manipulation
por: Amaro-Ortiz, Alexandra, et al.
Publicado: (2014)

Immunologic adverse reactions of β-blockers and the skin
por: Tatu, Alin Laurentiu, et al.
Publicado: (2019)

Carvedilol Versus Other Nonselective Beta Blockers for Variceal Bleeding Prophylaxis and Death: A Network Meta-analysis
por: Cheung, Ka-Shing, et al.
Publicado: (2023)

Recent Advances in Clinical Research for Skin Cancer Chemoprevention
por: Tow, Ruby, et al.
Publicado: (2023)

Coenzyme Q(10) Sunscreen Prevents Progression of Ultraviolet-Induced Skin Damage in Mice
por: Wu, Haiyou, et al.
Publicado: (2020)

Reply to: How carvedilol does not activate β(2)-adrenoceptors
por: Kostenis, Evi, et al.
Publicado: (2023)

Carvedilol in hypertension treatment
por: Stafylas, Panagiotis C, et al.
Publicado: (2008)

Carvedilol—NSBB of Choice in All Cirrhotics? Short Title: Carvedilol for Portal Hypertension
por: Tandon, Puneeta, et al.
Publicado: (2015)

Preventive role of carvedilol in adriamycin-induced cardiomyopathy
por: Jhorawat, Rajesh, et al.
Publicado: (2016)

Nanodiamonds protect skin from ultraviolet B-induced damage in mice
por: Wu, Meng-Si, et al.
Publicado: (2015)

Carvedilol in the treatment of chronic heart failure: Lessons from The Carvedilol Or Metoprolol European Trial
por: Kveiborg, Britt, et al.
Publicado: (2007)

NADPH Oxidase and Epidermal Growth Factor Receptor Are Promising Targets of Phytochemicals for Ultraviolet-Induced Skin Carcinogenesis
por: Kim, Min Jeong, et al.
Publicado: (2021)

Use of carvedilol in hypertension: an update
por: Leonetti, Gastone, et al.
Publicado: (2012)

Carvedilol in the Treatment of Portal Hypertension
por: Al-Ghamdi, Hamdan
Publicado: (2011)

Reconstructed Skin Models Revealed Unexpected Differences in Epidermal African and Caucasian Skin
por: Girardeau-Hubert, Sarah, et al.
Publicado: (2019)

GSK3β signaling is involved in ultraviolet B-induced activation of autophagy in epidermal cells
por: YANG, YANG, et al.
Publicado: (2012)

Derinat Protects Skin against Ultraviolet-B (UVB)-Induced Cellular Damage
por: Hsu, Wen-Li, et al.
Publicado: (2015)

Silver Nanoparticles Protect Skin from Ultraviolet B-Induced Damage in Mice
por: Ho, Yu-Yi, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_23b89e19ej4v3sth5f9589cl8k