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miR-21-5p Under-Expression in Patients with Obstructive Sleep Apnea Modulates Intermittent Hypoxia with Re-Oxygenation-Induced-Cell Apoptosis and Cytotoxicity by Targeting Pro-Inflammatory TNF-α-TLR4 Signaling

The purpose of this study is to explore the anti-inflammatory role of microRNAs (miR)-21 and miR-23 targeting the TLR/TNF-α pathway in response to chronic intermittent hypoxia with re-oxygenation (IHR) injury in patients with obstructive sleep apnea (OSA). Gene expression levels of the miR-21/23a, a...

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Detalles Bibliográficos
Autores principales:	Chen, Yung-Che, Hsu, Po-Yuan, Su, Mao-Chang, Chin, Chien-Hung, Liou, Chia-Wei, Wang, Ting-Ya, Lin, Yong-Yong, Lee, Chiu Ping, Lin, Meng-Chih, Hsiao, Chang-Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037842/ https://www.ncbi.nlm.nih.gov/pubmed/32028672 http://dx.doi.org/10.3390/ijms21030999

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