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Synthesis of Functionalized Cannabilactones

A new approach to synthesize cannabilactones using Suzuki cross-coupling reaction followed by one-step demethylation-cyclization is presented. The two key cannabilactone prototypes AM1710 and AM1714 were obtained selectively in high overall yields and in a lesser number of synthetic steps when compa...

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Detalles Bibliográficos
Autores principales: Liu, Yingpeng, Ho, Thanh C., Baradwan, Mohammed, Pascual Lopez-Alberca, Maria, Iliopoulos-Tsoutsouvas, Christos, Nikas, Spyros P., Makriyannis, Alexandros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037859/
https://www.ncbi.nlm.nih.gov/pubmed/32041131
http://dx.doi.org/10.3390/molecules25030684

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